Review ATI Pharmacology Exam 2

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ATI Pharmacology Exam 2

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Total Questions : 51

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Question 1:

A nurse is obtaining a medical history from a client who is to start warfarin therapy and currently uses herbal supplements at home. The nurse should inform the client that which of the following herbal supplements can interact adversely with warfarin?

A. Black cohosh B. Echinacea C. Feverfew D. Flaxseed

Answer and Explanation

Choice A:

Black cohosh is an herbal supplement that is used to treat menopausal symptoms, such as hot flashes and mood swings. It does not have a significant interaction with warfarin and does not affect the coagulation status of the client.

Choice B:

Echinacea is an herbal supplement that is used to boost the immune system and prevent or treat common colds and infections. It does not have a significant interaction with warfarin and does not affect the coagulation status of the client.

Choice C:

Feverfew is an herbal supplement that is used to treat migraines, arthritis, and fever. It has a significant interaction with warfarin and can increase the risk of bleeding and bruising. It can also reduce the effectiveness of warfarin and alter the client's international normalized ratio (INR).

Choice D:

Flaxseed is an herbal supplement that is used to lower cholesterol, blood pressure, and inflammation. It does not have a significant interaction with warfarin and does not affect the coagulation status of the client.

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Question 2:

A nurse in a coronary care unit is admitting a client who has had CPR following a cardiac arrest. The client is receiving lidocaine IV at 2 mg/min. When the client asks the nurse why he is receiving that medication, the nurse should explain that it has which of the following actions?

A. Prevents dysrhythmias B. Relieves pain C. Dissolves blood clots D. Slows intestinal motility

Answer and Explanation

Choice A:

Lidocaine is an antiarrhythmic medication that stabilizes the cardiac membrane and suppresses abnormal electrical impulses in the heart. It is used to treat ventricular dysrhythmias, such as ventricular tachycardia and ventricular fibrillation, which can occur after a cardiac arrest.

Choice B:

Lidocaine is not primarily used to relieve pain, although it has local anesthetic properties. It is not effective for chest pain caused by myocardial ischemia or infarction.

Choice C:

Lidocaine does not dissolve blood clots, nor does it prevent their formation. It has no anticoagulant or thrombolytic effects.

Choice D:

Lidocaine does not slow intestinal motility, nor does it affect the gastrointestinal system. It has no antispasmodic or antidiarrheal effects.

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Question 3:

A nurse in the emergency department is caring for a client who took 3 nitroglycerin tablets sublingually for chest pain. The client reports relief from the chest pain but now he is experiencing a headache. Which of the following statements should the nurse make?

A. A headache is likely due to the anxiety about the chest pain. B. A headache indicates tolerance to the medication. C. A headache is an expected adverse effect of the medication. D. A headache is an indication of an allergy to the medication.

Answer and Explanation

Choice A:

A headache is not likely due to the anxiety about the chest pain, as anxiety usually causes other symptoms, such as palpitations, sweating, or trembling. A headache is more likely related to the vasodilating action of nitroglycerin, which causes increased blood flow to the brain.

Choice B:

A headache does not indicate tolerance to the medication, as tolerance usually manifests as a reduced effect of the medication on relieving chest pain. A headache is more likely a sign of the medication's potency, as it indicates that the nitroglycerin is reaching the systemic circulation.

Choice C:

A headache is an expected adverse effect of the medication, as nitroglycerin causes vasodilation of the cerebral vessels, which can result in increased intracranial pressure and pain. A headache is usually mild and transient, and can be relieved by taking analgesics, such as acetaminophen.

Choice D:

A headache is not an indication of an allergy to the medication, as an allergic reaction usually causes other symptoms, such as rash, itching, swelling, or difficulty breathing. A headache is more likely a pharmacological effect of the medication, rather than an immunological response.

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Question 4:

A nurse is teaching a client who has a new prescription for hydrochlorothiazide for management of hypertension. Which of the following instructions should the nurse include?

A. Reduce intake of potassium-rich foods. B. Avoid grapefruit juice. C. Take this medication before bedtime. D. Monitor for leg cramps.

Answer and Explanation

Choice A:

Reducing intake of potassium-rich foods is not necessary for clients taking hydrochlorothiazide, as this medication can cause hypokalemia (low potassium levels) due to increased potassium excretion in the urine. Clients may need to increase their intake of potassium-rich foods or take potassium supplements to prevent hypokalemia.

Choice B:

Avoiding grapefruit juice is not necessary for clients taking hydrochlorothiazide, as this medication does not interact with grapefruit juice. Grapefruit juice can affect the metabolism of some other medications, such as statins, calcium channel blockers, and cyclosporine, by inhibiting the enzyme CYP3A4 in the liver.

Choice C:

Taking this medication before bedtime is not advisable for clients taking hydrochlorothiazide, as this medication can cause increased urination and nocturia (nighttime urination). Clients should take this medication in the morning or at least 6 hours before bedtime to avoid disrupting their sleep.

Choice D:

Monitoring for leg cramps is an important instruction for clients taking hydrochlorothiazide, as this medication can cause muscle cramps due to electrolyte imbalances, such as hypokalemia, hyponatremia (low sodium levels), or hypomagnesemia (low magnesium levels). Clients should report any signs of muscle cramps, weakness, or fatigue to their provider.

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Question 5:

A nurse is monitoring a client who is receiving a unit of packed RBCs following surgery. Which of the following assessments is an indication that the client might be experiencing a hemolytic reaction?

A. Vomiting B. Flushing C. Dyspnea D. Hypotension

Answer and Explanation

Choice A:

Vomiting is not a specific sign of a hemolytic reaction, as it can be caused by many other factors, such as anesthesia, infection, or medication. Vomiting may occur in other types of transfusion reactions, such as allergic or febrile reactions, but it is not indicative of hemolysis.

Choice B:

Flushing is not a specific sign of a hemolytic reaction, as it can be caused by many other factors, such as fever, infection, or medication. Flushing may occur in other types of transfusion reactions, such as allergic or febrile reactions, but it is not indicative of hemolysis.

Choice C:

Dyspnea is a specific sign of a hemolytic reaction, as it indicates that the client is experiencing respiratory distress due to the release of hemoglobin and its breakdown products into the bloodstream. Dyspnea may be accompanied by chest pain, cough, wheezes, or crackles. Dyspnea is a life-threatening symptom that requires immediate intervention.

Choice D:

Hypotension is not a specific sign of a hemolytic reaction, as it can be caused by many other factors, such as blood loss, dehydration, or medication. Hypotension may occur in other types of transfusion reactions, such as septic or anaphylactic reactions, but it is not indicative of hemolysis.

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Question 6:

A nurse is providing teaching to a client who has a new prescription for lisinopril. Which of the following statements by the nurse indicates an understanding of the teaching?

A. "I should take this medication with food." B. "I should expect to have facial swelling when taking this medication." C. "I should report a cough to my provider." D. "I should increase my intake of potassium-rich foods."

Answer and Explanation

Choice A:

Taking this medication with food is not necessary, as lisinopril can be taken with or without food. Food does not affect the absorption or effectiveness of lisinopril.

Choice B:

Facial swelling is not an expected effect of this medication, but a serious adverse reaction that indicates angioedema. Angioedema is a life-threatening condition that causes swelling of the face, tongue, throat, and airway. It requires immediate medical attention and discontinuation of lisinopril.

Choice C:

Reporting a cough to the provider is an important instruction, as a cough is a common and annoying side effect of lisinopril. Lisinopril belongs to the class of angiotensin-converting enzyme (ACE) inhibitors, which can cause a dry, persistent, nonproductive cough. The cough may interfere with the client's quality of life and adherence to the medication. The provider may prescribe an alternative medication, such as an angiotensin II receptor blocker (ARB), to avoid the cough.

Choice D:

Increasing the intake of potassium-rich foods is not advisable, as lisinopril can cause hyperkalemia (high potassium levels) due to decreased potassium excretion in the urine. Clients should monitor their potassium levels and avoid excessive intake of potassium supplements or foods, such as bananas, oranges, potatoes, and tomatoes.

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Question 7:

A charge nurse is supervising a newly licensed nurse who is caring for a client who is receiving a transfusion of packed RBCs. The nurse suspects a possible hemolytic reaction. After stopping the blood transfusion, which of the following actions by the new nurse requires intervention by the charge nurse?

A. The nurse collects a urine specimen. B. The nurse sends a blood specimen to the laboratory. C. The nurse initiates an infusion of 0.9% sodium chloride. D. The nurse starts the transfusion of another unit of blood product.

Answer and Explanation

Choice A:

The nurse collects a urine specimen is an appropriate action, as it can help detect the presence of hemoglobinuria, which is a sign of hemolysis. Hemoglobinuria is the excretion of hemoglobin in the urine, which can cause the urine to appear red or brown.

Choice B:

The nurse sends a blood specimen to the laboratory is an appropriate action, as it can help confirm the diagnosis of a hemolytic reaction and identify the cause. The laboratory can perform tests such as blood typing, cross-matching, direct antiglobulin test (DAT), and serum bilirubin.

Choice C:

The nurse initiates an infusion of 0.9% sodium chloride is an appropriate action, as it can help maintain the client's fluid and electrolyte balance and prevent hypovolemic shock. 0.9% sodium chloride is the preferred solution for blood transfusion reactions, as it is isotonic and compatible with blood products.

Choice D:

The nurse starts the transfusion of another unit of blood product is an inappropriate action, as it can worsen the client's condition and increase the risk of complications. The nurse should not resume the transfusion until the cause of the reaction is determined and the provider orders a new unit of blood product. The nurse should also return the unused blood product and tubing to the blood bank for analysis.

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Question 8:

A nurse is caring for a client who is on warfarin therapy for atrial fibrillation. The client's INR is 5.2. Which of the following medications should the nurse prepare to administer?

A. Atropine B. Epinephrine C. Vitamin K D. Protamine

Answer and Explanation

Choice A:

Atropine is not the correct answer, as it is an anticholinergic medication that is used to treat bradycardia, not warfarin overdose. Atropine has no effect on the INR or the coagulation cascade.

Choice B:

Epinephrine is not the correct answer, as it is a catecholamine medication that is used to treat anaphylaxis, cardiac arrest, or severe hypotension, not warfarin overdose. Epinephrine has no effect on the INR or the coagulation cascade.

Choice C:

Vitamin K is the correct answer, as it is the antidote for warfarin overdose. Vitamin K is a fat-soluble vitamin that is essential for the synthesis of clotting factors II, VII, IX, and X. Vitamin K can reverse the effects of warfarin and lower the INR to a therapeutic range.

Choice D:

Protamine is not the correct answer, as it is the antidote for heparin overdose, not warfarin overdose. Protamine is a protein that binds to and neutralizes heparin, but has no effect on warfarin or the INR.

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Question 9:

A nurse is caring for a client who has atrial fibrillation and receives digoxin daily. Before administering this medication, which of the following actions should the nurse take?

A. Weigh the client. B. Measure the client's blood pressure. C. Measure the client's apical pulse. D. Offer the client a light snack.

Answer and Explanation

Choice A:

Weighing the client is not a necessary action before administering digoxin, as it does not affect the dosage or effectiveness of the medication. Weighing the client may be important for monitoring fluid balance and edema, but it is not related to digoxin therapy.

Choice B:

Measuring the client's blood pressure is not a necessary action before administering digoxin, as it does not affect the dosage or effectiveness of the medication. Digoxin is not a blood pressure-lowering medication, but a cardiac glycoside that increases the contractility and efficiency of the heart. Measuring the blood pressure may be important for monitoring hypertension, but it is not related to digoxin therapy.

Choice C:

Measuring the client's apical pulse is a necessary action before administering digoxin, as it can help determine the safety and appropriateness of the medication. Digoxin can cause bradycardia (slow heart rate) as a side effect, which can be dangerous and symptomatic. The nurse should check the apical pulse for one full minute and withhold the medication if the pulse is below 60 beats per minute or above 100 beats per minute. The nurse should also report any abnormal or irregular rhythms to the provider.

Choice D:

Offering the client a light snack is not a necessary action before administering digoxin, as it does not affect the absorption or effectiveness of the medication. Digoxin can be taken with or without food. Offering the client a light snack may be important for maintaining nutrition and hydration, but it is not related to digoxin therapy.

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Question 10:

A nurse is assessing a client who has hypercholesterolemia and is receiving simvastatin. Which of the following findings should the nurse recognize as a potential adverse effect?

A. Blurred vision B. Orthostatic hypotension C. Urinary retention D. Muscle weakness

Answer and Explanation

Choice A:

Blurred vision is not a common or serious side effect of simvastatin, as it does not affect the eyes or the vision. Blurred vision may be caused by other factors, such as diabetes, hypertension, or eye disorders.

Choice B:

Orthostatic hypotension is not a common or serious side effect of simvastatin, as it does not affect the blood pressure or the vascular tone. Orthostatic hypotension may be caused by other factors, such as dehydration, anemia, or medication interactions.

Choice C:

Urinary retention is not a common or serious side effect of simvastatin, as it does not affect the urinary tract or the bladder function. Urinary retention may be caused by other factors, such as prostate enlargement, infection, or nerve damage.

Choice D:

Muscle weakness is a common and serious side effect of simvastatin, as it can indicate muscle damage or rhabdomyolysis. Rhabdomyolysis is a life-threatening condition that causes the breakdown of muscle tissue and the release of myoglobin into the bloodstream, which can lead to kidney failure. Muscle weakness may be accompanied by muscle pain, tenderness, or dark urine. The nurse should monitor the client's creatine kinase (CK) levels and report any signs of muscle damage to the provider.

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