Penicillin has cross-sensitivity to which of the following drug classes?
Aminoglycosides
Erythromycins
Quinolones
Cephalosporins
The Correct Answer is D
A. Aminoglycosides: Aminoglycosides are a different class of antibiotics. They do not have cross-sensitivity with penicillin. People who are allergic to penicillin can usually take aminoglycosides without a problem.
B. Erythromycins: Erythromycins are macrolide antibiotics. They are not related to penicillin structurally, so there is no cross-sensitivity between penicillin and erythromycins. People allergic to penicillin can generally take erythromycin without issues.
C. Quinolones: Quinolones, also known as fluoroquinolones, are a different class of antibiotics. They do not share a structural similarity with penicillin, so there is usually no cross-sensitivity between penicillin and quinolones. People allergic to penicillin can usually take quinolones without problems.
D. Cephalosporins: Cephalosporins are beta-lactam antibiotics, just like penicillins. They have a similar chemical structure to penicillins, which can lead to cross-sensitivity. Individuals who are allergic to penicillin might also have an allergic reaction to cephalosporins due to this structural resemblance. However, it's important to note that not all cephalosporins are the same, and the risk of cross-reactivity varies among different generations of cephalosporins. Healthcare providers need to assess the specific situation and choose an appropriate antibiotic if there is a known penicillin allergy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Most type-1 reactions are allergic: This statement is accurate. Type-1 hypersensitivity reactions are typically associated with allergies. When a person is exposed to a specific allergen (like pollen or certain foods), their immune system overreacts, leading to various symptoms, from mild to severe.
B. It is mediated by IgA: This statement is incorrect. Type-1 hypersensitivity reactions are primarily mediated by immunoglobulin E (IgE) antibodies. When these antibodies bind to allergens, they trigger the release of histamine and other chemicals, causing allergic symptoms.
C. It never contributes to autoimmune diseases: This statement is incorrect. While type-1 hypersensitivity reactions are often associated with allergies, they are distinct from autoimmune diseases. In autoimmune diseases, the immune system mistakenly attacks the body's own cells and tissues, which is a different mechanism from hypersensitivity reactions.
D. Most occur against medications: This statement is not entirely accurate. While some type-1 hypersensitivity reactions can be triggered by medications (like penicillin), they can also be caused by various other allergens such as pollen, animal dander, insect venom, and certain foods. The prevalence of medication-induced type-1 reactions varies, and it's not accurate to say that most occur against medications.
Correct Answer is C
Explanation
A. 8:00 AM: This time is too early to draw a trough level for a medication administered at 10:00 AM. The trough level should be drawn just before the next dose is given to get the lowest concentration in the bloodstream.
B. 11:00 AM: This time is after the scheduled dose of vancomycin at 10:00 AM. Waiting until 11:00 AM would not provide an accurate trough level because the patient has already received the medication.
C. 9:00 AM: This is the correct time to obtain the patient's blood sample. It is one hour before the scheduled dose of vancomycin at 10:00 AM. Drawing the trough level at this time ensures it reflects the lowest concentration of the drug in the bloodstream.
D. 12:00 noon: This time is after the scheduled dose of vancomycin at 10:00 AM. Waiting until noon would not provide an accurate trough level because the patient has already received the medication.
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