A nurse is teaching a nursing student what is meant by "generations" of cephalosporins. Which statement by the student indicates an understanding of the teaching?
"Cephalosporins are assigned to generations based on their relative costs to administer."
"Later generations of cephalosporins have lower resistance to destruction by beta-lactamases."
"Cephalosporins have increased activity against gram-negative bacteria with each new generation."
"First-generation cephalosporins have better penetration of the cerebrospinal fluid."
The Correct Answer is C
A. "Cephalosporins are assigned to generations based on their relative costs to administer."
This statement is incorrect. The classification of cephalosporins into generations is based on their antimicrobial spectrum and activity against specific bacteria, not their cost.
B. "Later generations of cephalosporins have lower resistance to destruction by beta-lactamases."
This statement is not accurate. In fact, later generations of cephalosporins have increased resistance to destruction by beta-lactamases, which are enzymes produced by bacteria that can break down certain antibiotics.
C. "Cephalosporins have increased activity against gram-negative bacteria with each new generation."
This statement is correct. Cephalosporins are grouped into generations (first to fifth) based on their antibacterial spectrum. As the generations progress, there is an increase in activity against gram-negative bacteria, among other improvements in their spectrum.
D. "First-generation cephalosporins have better penetration of the cerebrospinal fluid."
This statement is generally true. First-generation cephalosporins have better penetration into the cerebrospinal fluid, making them useful for treating certain central nervous system infections.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Neutrophils: Neutrophils are a type of white blood cell that plays a key role in the immune system's response to infections, particularly bacterial infections. They are not primarily involved in eliminating cancer cells.
B. Eosinophils: Eosinophils are another type of white blood cell. They are important in the immune response to parasites and are also involved in allergic reactions. While they have a role in the immune system, they are not the primary cells involved in eliminating cancer cells.
C. Platelets: Platelets, also known as thrombocytes, are not cells but rather small cell fragments. They are essential for blood clotting and do not directly participate in the immune response against cancer cells.
D. Macrophages: Macrophages are a type of white blood cell that are involved in the immune system's defense against cancer. They are phagocytes, which means they engulf and digest cellular debris, foreign substances, and cancer cells. Macrophages play a crucial role in the body's immune surveillance and response against cancer.
Correct Answer is B
Explanation
A. Antibiotics are prescribed according to culture and sensitivity reports:
When antibiotics are prescribed based on specific tests like cultures and sensitivity reports, it ensures that the right antibiotic is chosen for the specific bacteria causing the infection. This practice helps in targeting the infection more effectively, reducing the risk of antibiotic resistance.
B. Patients stop taking an antibiotic after they feel better:
This scenario is problematic. When patients start feeling better, they might assume the infection is completely gone and stop taking antibiotics before the prescribed course is finished. This premature discontinuation can leave some bacteria alive, which may develop resistance to the antibiotic used. This practice is a significant contributor to antibiotic resistance.
C. Antibiotics are taken with ascorbic acid (vitamin C):
Ascorbic acid (vitamin C) doesn't have a significant impact on antibiotic resistance. It is not a factor contributing to antibiotic resistance.
D. Antibiotics are taken with water or juice:
Whether antibiotics are taken with water or juice doesn’t directly influence antibiotic resistance. Proper hydration is essential to support the body's overall health, but it doesn't impact the development of antibiotic resistance.
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