Systemic lupus erythematosus is an example of which type of hypersensitivity reaction?
Type IV
Type III
Type II
Type I
The Correct Answer is B
A. Type IV Hypersensitivity (Delayed Hypersensitivity Reaction): This type of reaction involves a delayed immune response, typically occurring 24 to 72 hours after exposure to an antigen. It's characterized by the activation of T cells and macrophages, leading to inflammation. This type of hypersensitivity is often associated with conditions like contact dermatitis and some autoimmune diseases.
B. Type III Hypersensitivity (Antibody-Mediated Reaction): Type III hypersensitivity reactions occur when immune complexes, which are composed of antigens and antibodies, deposit in various tissues. This leads to inflammation and tissue damage. Systemic lupus erythematosus (SLE) is an example of a disease associated with Type III hypersensitivity.
C. Type II Hypersensitivity: This type of reaction involves antibodies (IgG or IgM) targeting antigens on the surface of cells. This can lead to cell destruction through various mechanisms, such as complement activation or antibody-dependent cell-mediated cytotoxicity (ADCC). Examples include hemolytic transfusion reactions and autoimmune hemolytic anemia.
D. Type I Hypersensitivity (Immediate Hypersensitivity Reaction): Type I hypersensitivity is characterized by an immediate immune response, typically occurring within minutes of exposure to an allergen. It involves the release of histamines and other mediators from mast cells and basophils, leading to symptoms like hives, respiratory distress, and anaphylaxis. Allergies, like hay fever and food allergies, are examples of Type I hypersensitivity reactions.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. "The antibiotic I have been taking doesn't work as well as it used to."
This statement shows awareness of decreased effectiveness, which can occur due to drug resistance. Bacteria can become resistant to antibiotics, leading to reduced efficacy of the medication over time.
B. "The bacteria in my body have become resilient."
This statement correctly attributes resistance to the bacteria. Resilience in this context means that bacteria have developed mechanisms to survive the effects of antibiotics, making the treatment less effective.
C. "Over time, an organism that had once been highly sensitive to an antibiotic may become less susceptible, or it may lose drug sensitivity entirely."
This statement accurately describes the concept of drug resistance. Bacteria can lose sensitivity to antibiotics, rendering the drugs ineffective against them.
D. "My body has become resistant to the antibiotic."
This statement is incorrect. It's the bacteria that develop resistance, not the patient's body. Patients don't become resistant to antibiotics; instead, bacteria evolve and adapt, making the drugs less effective against them.
Correct Answer is C
Explanation
A. Gentamicin: Gentamicin is an aminoglycoside antibiotic effective against many bacteria, but it's not the first choice for MRSA. Vancomycin or other alternatives are preferred due to the rising resistance of MRSA to gentamicin.
B. Nafcillin: Nafcillin is a penicillin antibiotic, often used for penicillin-sensitive staphylococcal infections. However, it is not effective against MRSA, which is resistant to many penicillin-based antibiotics.
C. Vancomycin: Vancomycin is a glycopeptide antibiotic used to treat a variety of bacterial infections, including MRSA. It works by inhibiting cell wall synthesis in bacteria, making it effective against Gram-positive bacteria that have developed resistance to other antibiotics like methicillin (which MRSA has).
D. Penicillin: Penicillin is a group of antibiotics that includes drugs like amoxicillin and ampicillin. MRSA is resistant to penicillin-based antibiotics, so they are not effective against MRSA infections.
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