Systemic lupus erythematosus is an example of which type of hypersensitivity reaction?
Type IV
Type III
Type II
Type I
The Correct Answer is B
A. Type IV Hypersensitivity (Delayed Hypersensitivity Reaction): This type of reaction involves a delayed immune response, typically occurring 24 to 72 hours after exposure to an antigen. It's characterized by the activation of T cells and macrophages, leading to inflammation. This type of hypersensitivity is often associated with conditions like contact dermatitis and some autoimmune diseases.
B. Type III Hypersensitivity (Antibody-Mediated Reaction): Type III hypersensitivity reactions occur when immune complexes, which are composed of antigens and antibodies, deposit in various tissues. This leads to inflammation and tissue damage. Systemic lupus erythematosus (SLE) is an example of a disease associated with Type III hypersensitivity.
C. Type II Hypersensitivity: This type of reaction involves antibodies (IgG or IgM) targeting antigens on the surface of cells. This can lead to cell destruction through various mechanisms, such as complement activation or antibody-dependent cell-mediated cytotoxicity (ADCC). Examples include hemolytic transfusion reactions and autoimmune hemolytic anemia.
D. Type I Hypersensitivity (Immediate Hypersensitivity Reaction): Type I hypersensitivity is characterized by an immediate immune response, typically occurring within minutes of exposure to an allergen. It involves the release of histamines and other mediators from mast cells and basophils, leading to symptoms like hives, respiratory distress, and anaphylaxis. Allergies, like hay fever and food allergies, are examples of Type I hypersensitivity reactions.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Neutrophils: Neutrophils are a type of white blood cell that plays a key role in the immune system's response to infections, particularly bacterial infections. They are not primarily involved in eliminating cancer cells.
B. Eosinophils: Eosinophils are another type of white blood cell. They are important in the immune response to parasites and are also involved in allergic reactions. While they have a role in the immune system, they are not the primary cells involved in eliminating cancer cells.
C. Platelets: Platelets, also known as thrombocytes, are not cells but rather small cell fragments. They are essential for blood clotting and do not directly participate in the immune response against cancer cells.
D. Macrophages: Macrophages are a type of white blood cell that are involved in the immune system's defense against cancer. They are phagocytes, which means they engulf and digest cellular debris, foreign substances, and cancer cells. Macrophages play a crucial role in the body's immune surveillance and response against cancer.
Correct Answer is B
Explanation
A. IgD: Immunoglobulin D (IgD) is found on the surface of B cells and serves as a receptor for antigen recognition during the immune response. Its exact function is not fully understood, but it plays a role in the activation of B cells.
B. IgE: Immunoglobulin E (IgE) is primarily associated with allergic responses and defense against parasitic infections. When an allergen enters the body, IgE antibodies trigger the release of histamine and other chemicals, leading to allergy symptoms. IgE is also involved in protecting against certain parasites.
C. IgG: Immunoglobulin G (IgG) is the most abundant immunoglobulin in the bloodstream. It provides long-term immunity by recognizing and neutralizing pathogens such as bacteria and viruses. IgG antibodies are involved in secondary immune responses and are transferred from mother to fetus, providing passive immunity.
D. IgM: Immunoglobulin M (IgM) is the first antibody produced during an initial immune response to an antigen. It is effective at agglutination (clumping) of pathogens. IgM antibodies are generally found in blood and lymph fluid and are the first line of defense during infections.
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