Your patient is on long-term prednisone therapy. This patient should have frequent follow-up office visits to assess for which of the following?

A. Reddened tongue and gums: This side effect is not typically associated with ampicillin. However, certain medications or medical conditions can cause changes in oral tissues, leading to redness in the tongue and gums.

B. Digit numbness and tingling: Ampicillin does not commonly cause numbness and tingling in the fingers and toes. These symptoms can be associated with neurological issues or circulatory problems.

C. Bruising and petechiae: These symptoms can indicate bleeding disorders or low platelet count and are not usually caused by ampicillin. It's essential to investigate further if a patient experiences unexplained bruising or petechiae.

D. Skin rash and loose stools: Skin rash is a known side effect of penicillin-type antibiotics, including ampicillin. Loose stools or diarrhea can also occur due to disruption of the gut flora caused by the antibiotic. Patients should be aware of these possibilities and report any severe or persistent symptoms to their healthcare provider.

A. Cushing's Syndrome: This is a condition caused by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. It is not related to kidney transplant or immunosuppressive therapy.

B. Hypersensitivity Reaction Type I: Also known as an immediate hypersensitivity reaction or an allergy, this type of reaction involves the immune system's exaggerated response to an allergen. Symptoms can range from mild to severe and occur quickly after exposure to the allergen. While allergies can cause various symptoms, they do not specifically represent rejection of a transplanted organ.

C. Chronic Graft Versus Host Rejection: This term is commonly associated with bone marrow or stem cell transplants. It occurs when immune cells from the donated tissue recognize the recipient's body as foreign and attack various organs or tissues. This process typically happens over a more extended period and is not directly related to the scenario described.

D. Acute Host Versus Graft Rejection: This occurs when the recipient's immune system recognizes the transplanted organ as foreign and launches an immune response against it. It can happen shortly after transplantation if the recipient's immune system is not adequately suppressed. In this case, stopping immunosuppressive therapy can trigger acute rejection, leading to the failure of the transplanted organ.