The nurse who is working in a pediatric unit administers tetracycline [Sumycin] to a preschool-age child. What is a potential adverse effect of the medication for this child?
Discoloration of teeth
Anabolic change
Cartilage damage
Suppression of growth
The Correct Answer is A
A. Discoloration of teeth: Tetracycline antibiotics can bind with calcium ions in teeth, leading to the development of yellow-gray-brown stains. This effect is particularly significant in developing teeth in children below the age of 8 and can result in permanent discoloration.
B. Anabolic change: This term doesn't specifically relate to the side effects of tetracycline. "Anabolic" generally refers to processes in the body that build up complex molecules from simpler ones. There's no direct connection between tetracycline and anabolic changes.
C. Cartilage damage: Tetracyclines, especially in high doses or with prolonged use, have been associated with potential adverse effects on cartilage. This is more relevant in individuals whose bones and cartilage are still growing, such as children. It can interfere with skeletal development.
D. Suppression of growth: Long-term use of tetracycline in children can interfere with bone growth and development. It can suppress the growth of bones and affect overall height. This is a significant concern when considering the use of tetracycline in pediatric patients.
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Related Questions
Correct Answer is A
Explanation
A. Discoloration of teeth: Tetracycline antibiotics can bind with calcium ions in teeth, leading to the development of yellow-gray-brown stains. This effect is particularly significant in developing teeth in children below the age of 8 and can result in permanent discoloration.
B. Anabolic change: This term doesn't specifically relate to the side effects of tetracycline. "Anabolic" generally refers to processes in the body that build up complex molecules from simpler ones. There's no direct connection between tetracycline and anabolic changes.
C. Cartilage damage: Tetracyclines, especially in high doses or with prolonged use, have been associated with potential adverse effects on cartilage. This is more relevant in individuals whose bones and cartilage are still growing, such as children. It can interfere with skeletal development.
D. Suppression of growth: Long-term use of tetracycline in children can interfere with bone growth and development. It can suppress the growth of bones and affect overall height. This is a significant concern when considering the use of tetracycline in pediatric patients.
Correct Answer is B
Explanation
A. Seizures: Some antibiotics, especially cephalosporins, can lower the seizure threshold, increasing the risk of seizures, especially in individuals prone to seizures or those with a history of epilepsy.
B. Nephrotoxicity: Both cephalosporins and aminoglycosides have the potential to harm the kidneys. When used together, their nephrotoxic effects can be additive, increasing the risk of kidney problems in patients.
C. Hearing Loss: Aminoglycosides, a class of antibiotics that includes drugs like gentamicin, are well-known for their potential to cause hearing loss, especially when used in high doses or for prolonged periods. This effect is due to their toxic impact on the hair cells in the inner ear.
D. Hepatotoxicity: Hepatotoxicity refers to liver damage caused by medications. Some antibiotics, including certain cephalosporins, can have hepatotoxic effects, potentially harming the liver. Monitoring liver function is important when these drugs are used.
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