Which immunoglobulin provides the most protection against Infection in a client, as it is the most abundant?
IgG
IgE
IgM
IgA
The Correct Answer is A
A. IgG: Immunoglobulin G (IgG) is the most abundant antibody in the bloodstream and represents about 75% of all the antibodies in the body. It provides long-term immunity because it can persist in the bloodstream for a long time. IgG antibodies are involved in secondary immune responses and are capable of crossing the placenta, providing passive immunity to newborns.
B. IgE: Immunoglobulin E (IgE) is associated mainly with allergic reactions. When the body is exposed to an allergen, it triggers the release of IgE, leading to the symptoms of an allergic response, such as sneezing or itching.
C. IgM: Immunoglobulin M (IgM) is the largest antibody and is usually the first antibody produced during an initial exposure to an antigen. It is particularly effective at agglutination (clumping together) of pathogens.
D. IgA: Immunoglobulin A (IgA) is found in high concentrations in mucous membranes, particularly those lining the respiratory passages and gastrointestinal tract. It provides localized defense against pathogens. IgA antibodies are also found in saliva, tears, and breast milk, providing immunity to infants.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. "Cephalosporins are assigned to generations based on their relative costs to administer."
This statement is incorrect. The classification of cephalosporins into generations is based on their antimicrobial spectrum and activity against specific bacteria, not their cost.
B. "Later generations of cephalosporins have lower resistance to destruction by beta-lactamases."
This statement is not accurate. In fact, later generations of cephalosporins have increased resistance to destruction by beta-lactamases, which are enzymes produced by bacteria that can break down certain antibiotics.
C. "Cephalosporins have increased activity against gram-negative bacteria with each new generation."
This statement is correct. Cephalosporins are grouped into generations (first to fifth) based on their antibacterial spectrum. As the generations progress, there is an increase in activity against gram-negative bacteria, among other improvements in their spectrum.
D. "First-generation cephalosporins have better penetration of the cerebrospinal fluid."
This statement is generally true. First-generation cephalosporins have better penetration into the cerebrospinal fluid, making them useful for treating certain central nervous system infections.
Correct Answer is A
Explanation
A. Most type-1 reactions are allergic: This statement is accurate. Type-1 hypersensitivity reactions are typically associated with allergies. When a person is exposed to a specific allergen (like pollen or certain foods), their immune system overreacts, leading to various symptoms, from mild to severe.
B. It is mediated by IgA: This statement is incorrect. Type-1 hypersensitivity reactions are primarily mediated by immunoglobulin E (IgE) antibodies. When these antibodies bind to allergens, they trigger the release of histamine and other chemicals, causing allergic symptoms.
C. It never contributes to autoimmune diseases: This statement is incorrect. While type-1 hypersensitivity reactions are often associated with allergies, they are distinct from autoimmune diseases. In autoimmune diseases, the immune system mistakenly attacks the body's own cells and tissues, which is a different mechanism from hypersensitivity reactions.
D. Most occur against medications: This statement is not entirely accurate. While some type-1 hypersensitivity reactions can be triggered by medications (like penicillin), they can also be caused by various other allergens such as pollen, animal dander, insect venom, and certain foods. The prevalence of medication-induced type-1 reactions varies, and it's not accurate to say that most occur against medications.
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