A nurse is teaching a client who has a new prescription for hydrochlorothiazide for management of hypertension. Which of the following instructions should the nurse include?
Reduce intake of potassium-rich foods.
Avoid grapefruit juice.
Take this medication before bedtime.
Monitor for leg cramps.
The Correct Answer is D
Choice A reason: Reducing intake of potassium-rich foods is not necessary for clients taking hydrochlorothiazide, as this medication can cause hypokalemia (low potassium levels) due to increased potassium excretion in the urine. Clients may need to increase their intake of potassium-rich foods or take potassium supplements to prevent hypokalemia.
Choice B reason: Avoiding grapefruit juice is not necessary for clients taking hydrochlorothiazide, as this medication does not interact with grapefruit juice. Grapefruit juice can affect the metabolism of some other medications, such as statins, calcium channel blockers, and cyclosporine, by inhibiting the enzyme CYP3A4 in the liver.
Choice C reason: Taking this medication before bedtime is not advisable for clients taking hydrochlorothiazide, as this medication can cause increased urination and nocturia (nighttime urination). Clients should take this medication in the morning or at least 6 hours before bedtime to avoid disrupting their sleep.
Choice D reason: Monitoring for leg cramps is an important instruction for clients taking hydrochlorothiazide, as this medication can cause muscle cramps due to electrolyte imbalances, such as hypokalemia, hyponatremia (low sodium levels), or hypomagnesemia (low magnesium levels). Clients should report any signs of muscle cramps, weakness, or fatigue to their provider.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
The correct answer is: d. The client uses garlic to lower cholesterol levels.
Choice A: The client follows a low-fat diet to reduce cholesterol
Following a low-fat diet to reduce cholesterol does not have a significant impact on the effects of warfarin. While diet can influence overall health and cholesterol levels, it does not directly interact with warfarin’s anticoagulant properties.
Choice B: The client drinks a glass of grapefruit juice every day
Grapefruit juice is known to interact with various medications by inhibiting the cytochrome P450 enzymes, particularly CYP3A4. However, grapefruit juice does not significantly affect warfarin metabolism. It is more commonly associated with interactions with statins and other medications.
Choice C: The client sprinkles flax seeds on food 1 hr before taking the anticoagulant
Flax seeds are rich in omega-3 fatty acids and fiber, which can be beneficial for heart health. However, there is no strong evidence to suggest that flax seeds significantly potentiate the effects of warfarin. They do not have a direct interaction with the anticoagulant properties of warfarin.
Choice D: The client uses garlic to lower cholesterol levels
Garlic is known to have antiplatelet properties, which can enhance the anticoagulant effects of warfarin. This can increase the risk of bleeding in clients taking warfarin. Garlic can interfere with the blood clotting process, making it a significant factor to consider when managing a client on warfarin.
Correct Answer is B
Explanation
Choice A reason: Ataxia is not a manifestation of digoxin toxicity, as it does not affect the coordination or balance of the client. Ataxia may be caused by other factors, such as cerebellar disorders, alcohol intoxication, or medication interactions.
Choice B reason: Anorexia is a manifestation of digoxin toxicity, as it affects the appetite and digestion of the client. Anorexia may be accompanied by nausea, vomiting, or abdominal pain, which are also signs of digoxin toxicity. Anorexia may lead to weight loss, dehydration, or electrolyte imbalance, which can worsen the condition of the client.

Choice C reason: Photosensitivity is not a manifestation of digoxin toxicity, as it does not affect the skin or the eyes of the client. Photosensitivity may be caused by other factors, such as sun exposure, allergies, or medication interactions.
Choice D reason: Jaundice is not a manifestation of digoxin toxicity, as it does not affect the liver or the bilirubin level of the client. Jaundice may be caused by other factors, such as liver disease, gallstones, or hemolysis.
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