A nurse is reviewing the medication record for a client who has chronic kidney disease. Which of the following medications should the nurse identify as having the potential to cause nephrotoxicity?

Ondansetron

Diphenhydramine

Vancomycin

Omeprazole

Answer and Explanation

The Correct Answer is C

A.   Ondansetron is an antiemetic commonly used to prevent nausea and vomiting, and it is not typically associated with nephrotoxicity.
B.   Diphenhydramine is an antihistamine used for allergy symptoms and as a sleep aid. It is not known to cause nephrotoxicity.
C.   Vancomycin is an antibiotic that can cause nephrotoxicity, especially when administered in high doses or in individuals with impaired renal function. Monitoring renal function is crucial when using vancomycin.
D.   Omeprazole is a proton pump inhibitor used to reduce gastric acid secretion and treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. It is not associated with nephrotoxicity.

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Correct Answer is A

Explanation

A. 0.45% sodium chloride, also known as half-normal saline, is a hypotonic solution with a lower concentration of sodium than normal serum levels. It can help to lower the sodium levels in a client with hypernatremia by diluting the excess sodium in the body.
B. Dextrose 10% in water is hypertonic and not appropriate for a client with hypernatremia, as it could exacerbate the imbalance.
C. Lactated Ringer's is isotonic and contains sodium in a similar concentration to serum levels, hence it could further increase the sodium levels.
D. Dextrose 5% in 0.9% sodium chloride (also known as D5NS) is a hypertonic solution that contains both dextrose and sodium. It would not be appropriate for a client with hypernatremia, as it could exacerbate the condition.

A. Obesity B. Protein in the urine C. Iron deficiency D. Dehydration

Correct Answer is D

Explanation

A. While obesity can contribute to certain health conditions, it is not a direct risk factor for the formation of renal calculi.
B. Proteinuria may indicate kidney dysfunction, but it is not a direct risk factor for the formation of renal calculi.
C. Iron deficiency is not directly associated with an increased risk of renal calculi formation.
D. Dehydration can lead to concentrated urine, which increases the risk of crystal formation and subsequently the formation of renal calculi.

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A nurse is reviewing the medication record for a client who has chronic kidney disease. Which of the following medications should the nurse identify as having the potential to cause nephrotoxicity?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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