A nurse is reviewing the medication record for a client who has chronic kidney disease. Which of the following medications should the nurse identify as having the potential to cause nephrotoxicity?
Ondansetron
Diphenhydramine
Vancomycin
Omeprazole
The Correct Answer is C
A. Ondansetron is an antiemetic commonly used to prevent nausea and vomiting, and it is not typically associated with nephrotoxicity.
B. Diphenhydramine is an antihistamine used for allergy symptoms and as a sleep aid. It is not known to cause nephrotoxicity.
C. Vancomycin is an antibiotic that can cause nephrotoxicity, especially when administered in high doses or in individuals with impaired renal function. Monitoring renal function is crucial when using vancomycin.
D. Omeprazole is a proton pump inhibitor used to reduce gastric acid secretion and treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. It is not associated with nephrotoxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Kernig's sign is a test for meningitis and is not related to the tingling sensation described by the client.
B. Chvostek's sign is a clinical sign of hypocalcemia, which can occur post-thyroidectomy due to inadvertent damage or removal of the parathyroid glands.
C. Babinski's sign is a test for upper motor neuron lesions and is not related to the tingling sensation described by the client.
D. Brudzinski's sign is a test for meningitis and is not related to the tingling sensation described by the client.

Correct Answer is C
Explanation
A. Respiratory acidosis typically presents with cool, clammy skin due to compensatory peripheral vasoconstriction.
B. Peripheral pulses may be weak or thready in respiratory acidosis due to decreased cardiac output.
C. Respiratory acidosis can lead to electrolyte imbalances, particularly hyperkalemia, which can manifest as widened QRS complexes on an electrocardiogram (ECG).
D. Respiratory acidosis can lead to hyperkalemia, but hyperactive deep tendon reflexes are not a characteristic finding.
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