A nurse is reviewing the medication record for a client who has chronic kidney disease. Which of the following medications should the nurse identify as having the potential to cause nephrotoxicity?
Ondansetron
Diphenhydramine
Vancomycin
Omeprazole
The Correct Answer is C
A. Ondansetron is an antiemetic commonly used to prevent nausea and vomiting, and it is not typically associated with nephrotoxicity.
B. Diphenhydramine is an antihistamine used for allergy symptoms and as a sleep aid. It is not known to cause nephrotoxicity.
C. Vancomycin is an antibiotic that can cause nephrotoxicity, especially when administered in high doses or in individuals with impaired renal function. Monitoring renal function is crucial when using vancomycin.
D. Omeprazole is a proton pump inhibitor used to reduce gastric acid secretion and treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. It is not associated with nephrotoxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Blood urea nitrogen (BUN) can be affected by factors other than renal function, such as hydration status and protein intake.
B. Serum creatinine is a more specific indicator of renal function because it reflects the glomerular filtration rate (GFR). Elevated levels indicate impaired renal function.
C. Urine-specific gravity can provide some information about renal concentrating ability but is not as specific or sensitive as serum creatinine for assessing overall renal function.
D. Serum sodium levels may be affected by various factors, including hydration status and medications, but they do not directly reflect renal function.
Correct Answer is C
Explanation
A. Dry skin is not a typical manifestation of respiratory acidosis.
B. Abdominal pain is not a typical manifestation of respiratory acidosis.
C. Lethargy and altered mental status are common manifestations of respiratory acidosis due to the effects of hypercapnia (elevated PaCO2) on the central nervous system.
D. Numbness of fingers is not a typical manifestation of respiratory acidosis.

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