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A nurse is assessing a client who is 2 weeks postoperative following a kidney transplant. Which of the following manifestations should the nurse identify as possible organ rejection?

Weight loss

Insomnia

Temperature 36.1°C (97.0° F)

Oliguria

Answer and Explanation

The Correct Answer is D

A. Weight loss is not typically a manifestation of organ rejection post kidney transplant.

B. Insomnia is not typically associated with organ rejection post kidney transplant.

C. Normal body temperature does not indicate organ rejection post kidney transplant.

D. Oliguria or decreased urine output can be a sign of organ rejection post kidney transplant due to decreased renal perfusion.

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Correct Answer is C

Explanation

A. Ondansetron is an antiemetic commonly used to prevent nausea and vomiting, and it is not typically associated with nephrotoxicity.
B. Diphenhydramine is an antihistamine used for allergy symptoms and as a sleep aid. It is not known to cause nephrotoxicity.
C. Vancomycin is an antibiotic that can cause nephrotoxicity, especially when administered in high doses or in individuals with impaired renal function. Monitoring renal function is crucial when using vancomycin.
D. Omeprazole is a proton pump inhibitor used to reduce gastric acid secretion and treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. It is not associated with nephrotoxicity.

A. Urine output of 50 mL in 4hr B. Respiratory rate of 16/min C. Diminished deep tendon reflexes D. Heart rate of 56/min

Correct Answer is B

Explanation

A. A urine output of 50 mL in 4 hours is inadequate and may indicate decreased renal perfusion. Magnesium sulfate can further compromise renal perfusion, so this finding warrants careful evaluation and potential adjustment of the infusion rate.
B. This indicates that the client is not experiencing respiratory depression, a potential side effect of magnesium sulfate toxicity.
C. Diminished deep tendon reflexes is an expected finding in magnesium sulfate toxicity.
D. A heart rate of 56/min is below the normal range for an adult but may be a common finding in clients receiving magnesium sulfate due to its cardiac depressant effects.

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A nurse is assessing a client who is 2 weeks postoperative following a kidney transplant. Which of the following manifestations should the nurse identify as possible organ rejection?

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