A nurse is reviewing laboratory values for a client who has systemic lupus erythematosus (SLE). Which of the following values should give the nurse the best indication of the client's renal function?

Choice A rationale:
Serum creatinine is a waste product that is produced by muscle metabolism and is normally excreted by the kidneys.
When kidney function is impaired, creatinine levels in the blood increase, making it a sensitive and specific indicator of renal function.
It is considered one of the most reliable markers for assessing kidney function and is routinely used to screen for and monitor kidney disease.

Choice B rationale:
Serum sodium is an electrolyte that is regulated by the kidneys, but it is not a direct measure of renal function. Sodium levels can be affected by various factors, including fluid intake, medications, and hormonal imbalances.
While abnormal sodium levels can sometimes be a sign of kidney dysfunction, they can also occur due to other conditions, making it less specific as an indicator of renal function.
Choice C rationale:

Blood urea nitrogen (BUN) is another waste product that is produced by the breakdown of proteins and is normally excreted by the kidneys.
However, BUN levels can be influenced by factors other than kidney function, such as dietary protein intake, dehydration, and gastrointestinal bleeding.
This makes BUN less specific than serum creatinine as a marker of renal function.

Choice D rationale:
Urine-specific gravity measures the concentration of solutes in urine, which can provide some information about kidney function.
However, it is not as sensitive or specific as serum creatinine.
Urine-specific gravity can be affected by factors such as fluid intake and hydration status, which can make it less reliable as an indicator of renal function.

Choice A rationale:
Candidiasis, also known as thrush, is a fungal infection caused by Candida albicans. It commonly affects the mouth, causing white patches on the tongue, inner cheeks, gums, or tonsils.
Individuals with AIDS often have weakened immune systems due to a decreased CD4 T-cell count. This makes them more susceptible to opportunistic infections like candidiasis.
The fungal infection can spread to the esophagus, causing difficulty swallowing, or even to the bloodstream, leading to more serious complications.
Choice B rationale:
Xerostomia refers to dry mouth. It can be caused by various factors, including medications, salivary gland dysfunction, or radiation therapy. While it can occur in individuals with AIDS, it's not directly linked to a decreased CD4 T-cell count.
Choice C rationale:
Halitosis, or bad breath, can have multiple causes, including poor oral hygiene, gum disease, or digestive issues. It's not specifically associated with AIDS or a decreased CD4 T-cell count.
Choice D rationale:
Gingivitis is inflammation of the gums, often caused by plaque buildup. It's a common condition, but it's not directly linked to AIDS or a decreased CD4 T-cell count.