Which type of immunodeficiency disorder is characterized by a deficiency in immunoglobulin A (Ig
a. Selective IgM deficiency
X-linked agammaglobulinemia
Common variable immunodeficiency (CVID)
Selective IgA deficiency
The Correct Answer is D
Explanation: The correct answer is d. Selective IgA deficiency. This disorder is characterized by a lack of immunoglobulin A, which can lead to an increased susceptibility to infections, particularly in the respiratory and gastrointestinal tracts.
Incorrect choices:
a. Selective IgM deficiency is a rare immunodeficiency disorder characterized by a lack of immunoglobulin M (IgM), not IgA.
b. X-linked agammaglobulinemia is a primary immunodeficiency disorder caused by a mutation in the BTK gene, resulting in a deficiency of B cells and immunoglobulins.
c. Common variable immunodeficiency (CVID) is a heterogeneous group of disorders characterized by decreased levels of immunoglobulins, including IgA, IgG, and IgM.
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Related Questions
Correct Answer is A
Explanation
Explanation: The correct answer is a. Complete blood count (CBC) with differential. A CBC with differential is a standard diagnostic test used to assess the levels of different blood cells, including white blood cells, which are crucial for the immune system. Abnormalities in the white blood cell count and differential can indicate potential immunodeficiency.
Incorrect choices:
b. A chest X-ray is not a specific diagnostic test for immunodeficiency disorders. It is typically used to assess the condition of the lungs and chest organs.
c. An electrocardiogram (ECG) is a test used to assess the electrical activity of the heart and is not related to the diagnosis of immunodeficiency disorders.
d. A urinalysis is a test used to assess the urine for various abnormalities and is not specific to diagnosing immunodeficiency disorders.
Correct Answer is C
Explanation
Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.
Incorrect choices:
a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.
b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.
d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.
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