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Which type of immunodeficiency disorder is characterized by a deficiency in immunoglobulin A (Ig

A.

a. Selective IgM deficiency

B.

X-linked agammaglobulinemia

C.

Common variable immunodeficiency (CVID)

D.

Selective IgA deficiency

Answer and Explanation

The Correct Answer is D

Explanation: The correct answer is d. Selective IgA deficiency. This disorder is characterized by a lack of immunoglobulin A, which can lead to an increased susceptibility to infections, particularly in the respiratory and gastrointestinal tracts.

Incorrect choices:

a. Selective IgM deficiency is a rare immunodeficiency disorder characterized by a lack of immunoglobulin M (IgM), not IgA.

b. X-linked agammaglobulinemia is a primary immunodeficiency disorder caused by a mutation in the BTK gene, resulting in a deficiency of B cells and immunoglobulins.

c. Common variable immunodeficiency (CVID) is a heterogeneous group of disorders characterized by decreased levels of immunoglobulins, including IgA, IgG, and IgM.


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Related Questions

Correct Answer is C

Explanation

Explanation: The correct answer is c. Chronic diarrhea. Primary immunodeficiency disorders can affect the gastrointestinal system, leading to chronic diarrhea due to frequent infections and inflammation.

Incorrect choices:

a. Unexplained weight loss is not a specific symptom of primary immunodeficiency disorders. It may be seen in various other medical conditions, such as cancer or metabolic disorders.

b. Recurrent skin rashes are not a characteristic symptom of primary immunodeficiency disorders. Skin rashes may be caused by allergic reactions or dermatological conditions.

d. Difficulty falling asleep is not typically associated with primary immunodeficiency disorders. It may be related to sleep disorders or anxiety.

Correct Answer is A

Explanation

Explanation: The correct answer is a. Severe combined immunodeficiency (SCID). SCID is a severe and rare primary immunodeficiency disorder characterized by the absence or severe impairment of both T and B cells, leading to a profound deficiency in cellular and humoral immunity.

Incorrect choices:

b. X-linked agammaglobulinemia (XLA) primarily affects B-cell function, resulting in a lack of mature B cells and low levels of immunoglobulins, but does not typically involve T-cell deficiency.

c. Wiskott-Aldrich syndrome affects platelet function and immune system regulation, but it is not characterized by a deficiency of both T and B cells.

d. Common variable immunodeficiency (CVID) is characterized by reduced levels of immunoglobulins, particularly IgG and IgA, but it does not typically lead to a complete deficiency of both T and B cells.

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