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Which type of immunodeficiency disorder is characterized by a deficiency in immunoglobulin A (Ig

A.

a. Selective IgM deficiency

B.

X-linked agammaglobulinemia

C.

Common variable immunodeficiency (CVID)

D.

Selective IgA deficiency

Answer and Explanation

The Correct Answer is D

Explanation: The correct answer is d. Selective IgA deficiency. This disorder is characterized by a lack of immunoglobulin A, which can lead to an increased susceptibility to infections, particularly in the respiratory and gastrointestinal tracts.

Incorrect choices:

a. Selective IgM deficiency is a rare immunodeficiency disorder characterized by a lack of immunoglobulin M (IgM), not IgA.

b. X-linked agammaglobulinemia is a primary immunodeficiency disorder caused by a mutation in the BTK gene, resulting in a deficiency of B cells and immunoglobulins.

c. Common variable immunodeficiency (CVID) is a heterogeneous group of disorders characterized by decreased levels of immunoglobulins, including IgA, IgG, and IgM.


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Related Questions

Correct Answer is B

Explanation

Explanation: The correct answer is b. Persistent fever and night sweats. Fever and night sweats are common clinical manifestations of immunodeficiency disorders. The immune system's inability to fight off infections can lead to recurrent fevers and night sweats as the body tries to combat pathogens.

Incorrect choices:

a. Hyperactivity and restlessness are not typical clinical manifestations of immunodeficiency disorders. These symptoms are more commonly associated with conditions affecting the central nervous system.

c. Weight gain and increased appetite are not typical clinical manifestations of immunodeficiency disorders. They may be seen in conditions like hypothyroidism or hormonal imbalances.

d. Elevated blood pressure is not a common clinical manifestation of immunodeficiency disorders. It may be seen in conditions like hypertension or cardiovascular disorders.

Correct Answer is D

Explanation

Explanation: The correct answer is d. Immunoglobulin levels. Immunoglobulin levels, specifically IgG, IgM, and IgA, are commonly measured to assess immune function and identify deficiencies in immunoglobulin production. Abnormalities in immunoglobulin levels can indicate the presence of an immunodeficiency disorder.

Incorrect choices:

a. A complete blood count (CBC) provides information about various blood components, such as red blood cells, white blood cells, and platelets, but it does not specifically assess immune function.

b. A chest X-ray may be used to evaluate the condition of the lungs and detect infections, but it is not a specific test for immunodeficiency disorders.

c. Allergy skin testing is used to diagnose allergies and assess the body's response to allergens, but it is not a diagnostic test for immunodeficiency disorders.

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