Which of the following statements is true regarding immunodeficiency disorders?

Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.

Incorrect choices:

a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.

b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.

d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.

Explanation: The correct answer is b. Persistent fever and night sweats. Fever and night sweats are common clinical manifestations of immunodeficiency disorders. The immune system's inability to fight off infections can lead to recurrent fevers and night sweats as the body tries to combat pathogens.

Incorrect choices:

a. Hyperactivity and restlessness are not typical clinical manifestations of immunodeficiency disorders. These symptoms are more commonly associated with conditions affecting the central nervous system.

c. Weight gain and increased appetite are not typical clinical manifestations of immunodeficiency disorders. They may be seen in conditions like hypothyroidism or hormonal imbalances.

d. Elevated blood pressure is not a common clinical manifestation of immunodeficiency disorders. It may be seen in conditions like hypertension or cardiovascular disorders.