Which type of immunodeficiency disorder is inherited in an X-linked recessive pattern and primarily affects males, leading to the absence of mature B cells and immunoglobulins?
Selective IgA deficiency
DiGeorge syndrome
X-linked agammaglobulinemia
Severe combined immunodeficiency (SCID)
The Correct Answer is C
Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.
Incorrect choices:
a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.
b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.
d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.
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Related Questions
Correct Answer is C
Explanation
Explanation: The correct answer is c. Serum immunoglobulin levels. A primary immunodeficiency disorder often results in abnormal levels of immunoglobulins (antibodies) in the blood. Measuring serum immunoglobulin levels can help identify potential deficiencies and guide the diagnosis of primary immunodeficiency disorders.
Incorrect choices:
a. Enzyme-linked immunosorbent assay (ELISA) is a test used to detect specific antibodies or antigens in the blood, but it is not specific to diagnosing primary immunodeficiency disorders.
b. A chest X-ray is not a specific test for diagnosing primary immunodeficiency disorders. It is typically used to assess the condition of the lungs and chest organs.
d. A complete blood count (CBC) is a general blood test that may reveal abnormalities in white blood cell count but does not specifically assess immunoglobulin levels.
Correct Answer is C
Explanation
Explanation: The correct answer is c. Primary immunodeficiency disorders are typically present at birth or during early childhood and are caused by genetic defects that affect the function of the immune system. They are not acquired later in life due to environmental factors.
Incorrect choices:
a. Primary immunodeficiency disorders are not acquired later in life; they are usually genetic and present from birth.
b. Primary immunodeficiency disorders are characterized by a weakened or deficient immune response, not an overactive immune response.
d. Primary immunodeficiency disorders are often not easily treatable with antibiotics and antiviral medications because they result from genetic defects in the immune system.
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