Which type of immunodeficiency disorder is inherited in an X-linked recessive pattern and primarily affects males, leading to the absence of mature B cells and immunoglobulins?
Selective IgA deficiency
DiGeorge syndrome
X-linked agammaglobulinemia
Severe combined immunodeficiency (SCID)
The Correct Answer is C
Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.
Incorrect choices:
a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.
b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.
d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.
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Correct Answer is D
Explanation
Explanation: The correct answer is d. Absence or significantly reduced T cell levels. Severe combined immunodeficiency (SCID) is characterized by a severe deficiency or absence of T cells, which are essential for cell-mediated immunity.
Incorrect choices:
a. Increased levels of circulating B cells are not characteristic of SCID. In SCID, both T and B cell immunity are affected, and the client may have reduced levels of both.
b. Elevated immunoglobulin M (IgM) levels may occur in certain types of immunodeficiency disorders, but it is not a specific finding for SCID.
c. Abnormal antibody response to vaccinations can be observed in various immunodeficiency disorders, but it does not specifically indicate SCID.
Correct Answer is C
Explanation
Explanation: The correct answer is c. "It's essential for me to receive all recommended vaccines, including live vaccines." Clients with primary immunodeficiency disorders should not receive live vaccines, as they can cause severe infections in this population. Only inactivated vaccines are recommended to avoid the risk of vaccine-associated infections.
Incorrect choices:
a. Avoiding contact with sick individuals is crucial for clients with primary immunodeficiency disorders to minimize the risk of acquiring infections.
b. Taking prescribed immunoglobulin therapy as scheduled is an important treatment for clients with primary immunodeficiency disorders to boost their immune response and prevent infections.
d. Reporting any signs of infection or illness promptly to the healthcare provider is essential for early detection and treatment of infections in clients with primary immunodeficiency disorders.
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