Which type of immunodeficiency disorder is inherited in an X-linked recessive pattern and primarily affects males, leading to the absence of mature B cells and immunoglobulins?
Selective IgA deficiency
DiGeorge syndrome
X-linked agammaglobulinemia
Severe combined immunodeficiency (SCID)
The Correct Answer is C
Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.
Incorrect choices:
a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.
b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.
d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.
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Related Questions
Correct Answer is C
Explanation
Explanation: The correct answer is c. Frequent and severe infections are common clinical manifestations of immunodeficiency disorders. The weakened immune system is unable to effectively defend against infections, leading to recurrent and severe infections.
Incorrect choices:
a. Severe allergic reactions are more characteristic of allergies or hypersensitivity disorders, not immunodeficiency disorders.
b. Chronic inflammation can be seen in various conditions, but it is not a specific clinical manifestation of immunodeficiency disorders.
d. Autoimmune diseases result from an overactive immune response attacking the body's own tissues, which is the opposite of immunodeficiency disorders where the immune system is weakened and unable to adequately protect against infections.
Correct Answer is D
Explanation
Explanation: The correct answer is d. Flow cytometry for lymphocyte subsets. Flow cytometry is a diagnostic test used to analyze the quantity and types of lymphocytes in the blood, which helps identify abnormalities in the immune system and diagnose immunodeficiency disorders.
Incorrect choices:
a. A complete blood count (CBC) provides general information about the client's overall blood cell counts, but it does not specifically diagnose immunodeficiency disorders.
b. Urinalysis is used to assess kidney function and identify urinary tract infections but is not a specific test for diagnosing immunodeficiency disorders.
c. Skin testing for allergies is performed to identify allergic reactions to specific allergens and is not used to diagnose immunodeficiency disorders.
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