Which type of immunodeficiency disorder is inherited in an X-linked recessive pattern and primarily affects males, leading to the absence of mature B cells and immunoglobulins?
Selective IgA deficiency
DiGeorge syndrome
X-linked agammaglobulinemia
Severe combined immunodeficiency (SCID)
The Correct Answer is C
Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.
Incorrect choices:
a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.
b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.
d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.
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Related Questions
Correct Answer is B
Explanation
Explanation: The correct answer is b. Recurrent skin infections. Recurrent skin infections are common clinical manifestations of immunodeficiency disorders in the elderly. The weakened immune system makes the skin more susceptible to infections and delays wound healing.
Incorrect choices:
a. Impaired balance and coordination are more commonly associated with neurological disorders or conditions affecting the musculoskeletal system, not immunodeficiency disorders.
c. Vision changes and blindness may be seen in conditions affecting the eyes or the visual system but are not typical clinical manifestations of immunodeficiency disorders.
d. Hearing loss is more commonly associated with conditions affecting the ears or the auditory system and is not a typical clinical manifestation of immunodeficiency disorders.
Correct Answer is C
Explanation
Explanation: The correct answer is c. Flow cytometry. Flow cytometry is a specialized test used to analyze the different cell types in a blood sample. In the case of SCID, flow cytometry can help identify the absence or severe deficiency of T cells and B cells, which are essential components of the immune system.
Incorrect choices:
a. A tuberculin skin test (TST) is used to detect exposure to tuberculosis (TB) and is not specific to diagnosing SCID.
b. A Western blot test is a type of immunoassay used to detect specific antibodies or antigens in the blood but is not specific to diagnosing SCID.
d. Liver function tests are used to assess the health of the liver and are not specific to diagnosing SCID.
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