Which of the following is not a common symptom of immunodeficiency disorders?

Explanation: The correct answer is b. Primary immunodeficiency disorders result from a genetic or inherited defect, while secondary immunodeficiency disorders are caused by external factors, such as infections or medications.

Incorrect choices:

a. Primary immunodeficiency disorders are present from birth and are usually genetic or inherited, while secondary immunodeficiency disorders can be acquired later in life due to external factors.

c. The manifestations and systems affected by primary and secondary immunodeficiency disorders can vary widely and are not limited to specific areas of the body.

d. Secondary immunodeficiency disorders are more common than primary immunodeficiency disorders, as they can be caused by various factors and are often associated with other medical conditions.

Explanation: The correct answer is c. Severe combined immunodeficiency (SCID). SCID is a group of rare genetic disorders that affect both T cells and B cells, resulting in a severe impairment of the immune system. Individuals with SCID are highly susceptible to infections and may need to live in a protected environment to avoid exposure to pathogens, hence the term "bubble boy disease."

Incorrect choices:

a. DiGeorge syndrome is a primary immunodeficiency disorder characterized by abnormalities in the development of certain organs, including the thymus, leading to impaired T cell function, but it does not affect B cell function.

b. X-linked agammaglobulinemia is a primary immunodeficiency disorder characterized by a lack of mature B cells and an inability to produce antibodies, but it does not affect T cell function.

d. Acquired immunodeficiency syndrome (AIDS) is a secondary immunodeficiency disorder caused by the human immunodeficiency virus (HIV) infection, which specifically targets and destroys CD4+ T cells, but it does not affect B cell function.