Which type of immunodeficiency disorder is characterized by a lack of mature B cells and an inability to produce antibodies?
DiGeorge syndrome
X-linked agammaglobulinemia
Severe combined immunodeficiency (SCID)
Acquired immunodeficiency syndrome (AIDS)
The Correct Answer is B
Explanation: The correct answer is b. X-linked agammaglobulinemia. X-linked agammaglobulinemia is a primary immunodeficiency disorder caused by a genetic mutation that leads to the absence of mature B cells, resulting in an inability to produce antibodies (immunoglobulins). As a result, individuals with this disorder are highly susceptible to infections, especially bacterial infections.
Incorrect choices:
a. DiGeorge syndrome is a primary immunodeficiency disorder characterized by abnormalities in the development of certain organs, including the thymus, leading to impaired T cell function.
c. Severe combined immunodeficiency (SCID) is a group of rare genetic disorders that affect both T cells and B cells, resulting in a severe impairment of the immune system.
d. Acquired immunodeficiency syndrome (AIDS) is a secondary immunodeficiency disorder caused by the human immunodeficiency virus (HIV) infection, which specifically targets and destroys CD4+ T cells, weakening the immune system's ability to fight infections.
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Related Questions
Correct Answer is C
Explanation
Explanation: The correct answer is c. Primary immunodeficiency disorders are typically present at birth or during early childhood and are caused by genetic defects that affect the function of the immune system. They are not acquired later in life due to environmental factors.
Incorrect choices:
a. Primary immunodeficiency disorders are not acquired later in life; they are usually genetic and present from birth.
b. Primary immunodeficiency disorders are characterized by a weakened or deficient immune response, not an overactive immune response.
d. Primary immunodeficiency disorders are often not easily treatable with antibiotics and antiviral medications because they result from genetic defects in the immune system.
Correct Answer is C
Explanation
Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.
Incorrect choices:
a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.
b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.
d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.
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