Which type of immunodeficiency disorder is characterized by a lack of mature B cells and an inability to produce antibodies?
DiGeorge syndrome
X-linked agammaglobulinemia
Severe combined immunodeficiency (SCID)
Acquired immunodeficiency syndrome (AIDS)
The Correct Answer is B
Explanation: The correct answer is b. X-linked agammaglobulinemia. X-linked agammaglobulinemia is a primary immunodeficiency disorder caused by a genetic mutation that leads to the absence of mature B cells, resulting in an inability to produce antibodies (immunoglobulins). As a result, individuals with this disorder are highly susceptible to infections, especially bacterial infections.
Incorrect choices:
a. DiGeorge syndrome is a primary immunodeficiency disorder characterized by abnormalities in the development of certain organs, including the thymus, leading to impaired T cell function.
c. Severe combined immunodeficiency (SCID) is a group of rare genetic disorders that affect both T cells and B cells, resulting in a severe impairment of the immune system.
d. Acquired immunodeficiency syndrome (AIDS) is a secondary immunodeficiency disorder caused by the human immunodeficiency virus (HIV) infection, which specifically targets and destroys CD4+ T cells, weakening the immune system's ability to fight infections.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Explanation: The correct answer is c. Failure to thrive. SCID is a severe form of immunodeficiency that affects multiple components of the immune system, leading to recurrent and severe infections and failure to thrive in affected infants.
Incorrect choices:
a. Recurrent ear infections are more commonly seen in other types of immunodeficiency disorders, such as selective IgA deficiency.
b. Chronic fatigue and lethargy may be seen in various medical conditions but are not specific to SCID.
d. Persistent joint pain is not a characteristic symptom of SCID. It may be associated with other autoimmune or inflammatory conditions.
Correct Answer is A
Explanation
Explanation: The correct answer is a. Complete blood count (CBC) with differential. A CBC with differential is a standard diagnostic test used to assess the levels of different blood cells, including white blood cells, which are crucial for the immune system. Abnormalities in the white blood cell count and differential can indicate potential immunodeficiency.
Incorrect choices:
b. A chest X-ray is not a specific diagnostic test for immunodeficiency disorders. It is typically used to assess the condition of the lungs and chest organs.
c. An electrocardiogram (ECG) is a test used to assess the electrical activity of the heart and is not related to the diagnosis of immunodeficiency disorders.
d. A urinalysis is a test used to assess the urine for various abnormalities and is not specific to diagnosing immunodeficiency disorders.
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