Which of the following is a potential complication of primary immunodeficiency disorders?

Explanation: The correct answer is d. Maintain strict hand hygiene and utilize protective equipment when providing care. Children with severe combined immunodeficiency (SCID) have a severely compromised immune system, making them highly susceptible to infections. Strict hand hygiene and the use of protective equipment, such as gloves and masks, are essential in preventing the transmission of infections to the child.

Incorrect choices:

a. Placing the child on contact precautions may not be sufficient to protect them from infections due to their high susceptibility. Additional precautions, such as strict hand hygiene and protective equipment, should be implemented.

b. Encouraging the child to play with other children may increase the risk of exposure to infections. Children with SCID should be protected from contact with potential sources of infection.

c. Live attenuated vaccines are contraindicated for children with SCID, as they can cause severe infections. Only inactivated vaccines are recommended to avoid the risk of vaccine-associated infections.

Explanation: The correct answer is a. Severe combined immunodeficiency (SCID). SCID is a severe and rare primary immunodeficiency disorder characterized by the absence or severe impairment of both T and B cells, leading to a profound deficiency in cellular and humoral immunity.

Incorrect choices:

b. X-linked agammaglobulinemia (XLA) primarily affects B-cell function, resulting in a lack of mature B cells and low levels of immunoglobulins, but does not typically involve T-cell deficiency.

c. Wiskott-Aldrich syndrome affects platelet function and immune system regulation, but it is not characterized by a deficiency of both T and B cells.

d. Common variable immunodeficiency (CVID) is characterized by reduced levels of immunoglobulins, particularly IgG and IgA, but it does not typically lead to a complete deficiency of both T and B cells.