Which laboratory test measures the effectiveness of warfarin?
PTT.
PT/INR.
aPTT.
ACT.
The Correct Answer is B
PT stands for prothrombin time, which is a measure of how long it takes the blood to clot.
INR stands for international normalized ratio, which is a way of standardizing the PT results across different laboratories.
Warfarin is a blood thinner that works by inhibiting the production of vitamin K-dependent clotting factors in the liver.
Therefore, warfarin prolongs the PT and increases the INR. The PT/INR test is used to monitor the effectiveness of warfarin therapy and adjust the dose accordingly.
Choice A is wrong because PTT stands for partial thromboplastin time, which is another measure of blood clotting time, but it reflects the activity of different clotting factors than PT. PTT is used to monitor heparin therapy, not warfarin therapy.
Choice C is wrong because aPTT stands for activated partial thromboplastin time, which is a variation of PTT that uses an activator to speed up the clotting time. Like PTT, aPTT is used to monitor heparin therapy, not warfarin therapy.
Choice D is wrong because ACT stands for activated clotting time, which is a measure of the whole blood clotting time. ACT is used to monitor high-dose heparin therapy during certain procedures, such as cardiac bypass surgery or angioplasty.
The normal ranges for these tests may vary depending on the laboratory and the method used, but generally, they are:
• PT: 10 to 13 seconds
• INR: 0.8 to 1.2 (without warfarin) or 2.0 to 3.0 (with warfarin)
• PTT: 25 to 35 seconds
• aPTT: 30 to 40 seconds
• ACT: 70 to 120 seconds
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Bile acid-binding resins are cholesterol-lowering agents that bind to bile acids in the intestine and prevent their reabsorption. This reduces the amount of bile acids available for cholesterol synthesis in the liver, which lowers the levels of LDL cholesterol in the blood. However, bile acids are also needed for the absorption of fat-soluble vitamins A, D, E, and K.Therefore, patients taking bile acid-binding resins may require supplements of these vitamins to prevent deficiency.
Choice A is wrong because nicotinic acid, or niacin, is a B vitamin that can lower cholesterol by limiting the production of fats in the liver.It does not affect the absorption of fat-soluble vitamins.
Choice B is wrong because nitroglycerin is not a cholesterol-lowering agent, but a vasodilator that relaxes the blood vessels and improves blood flow.It has no effect on fat-soluble vitamin absorption.
Choice D is wrong because beta blockers are not cholesterol-lowering agents, but drugs that lower blood pressure and heart rate by blocking the effects of adrenaline.They have no effect on fat-soluble vitamin absorption.
Correct Answer is D
Explanation
According to the International Society of Hypertension, lifestyle interventions are recommended for three to six months before medication in patients with grade 1 hypertension (BP < 160/100 mm Hg) and no comorbidities.Diet and exercise can lower BP by reducing weight, sodium intake, alcohol consumption, and stress levels.
Choice A is wrong because angiotensin-converting enzyme (ACE) inhibitors are not the first-line medication for hypertension in the general population.They are preferred in patients with diabetes, chronic kidney disease, or heart failure.
Choice B is wrong because combination diuretics are not the initial recommendation for hypertension.They are used when monotherapy is not sufficient to achieve the target BP or when there is fluid retention.
Choice C is wrong because beta-adrenergic blocking agents are not the first-line medication for hypertension in the general population.They are preferred in patients with ischemic heart disease, heart failure, or arrhythmias.
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