Which of the following anti-lipidemic drugs are the most potent antilipidemic agents, and have proven to lower the risk of Myocardial Infarction?
Atorvastatin.
Niacin.
Gemfibrozil
Amlodipine.
The Correct Answer is A
Atorvastatin is a type of statin, which are the most potent antilipidemic agents, and have proven to lower the risk of myocardial infarction by reducing the levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the blood. Statins also slightly increase the level of high-density lipoprotein (HDL) cholesterol, which is beneficial for cardiovascular health.
Choice B, niacin, is a type of nicotinic acid, which can lower LDL cholesterol and triglycerides, and increase HDL cholesterol, but it is less effective than statins and has more side effects, such as flushing, itching, and liver toxicity.
Choice C, gemfibrozil, is a type of fibric acid derivative, which can lower triglycerides and increase HDL cholesterol, but have little effect on LDL cholesterol. They are mainly used for patients with high triglyceride levels or low HDL cholesterol levels.
Choice D, amlodipine, is not an antilipidemic agent at all. It is a type of calcium channel blocker, which is used to treat hypertension and angina by relaxing the blood vessels and reducing the workload of the heart.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Intermittent claudication is a condition in which leg pain is produced upon increased activity and ischemia to tissues, but then the pain is reduced with rest. This is because the blood flow to the leg muscles is insufficient to meet the increased demand during exercise, but adequate at rest.Intermittent claudication is a common symptom of peripheral artery disease (PAD), which is a narrowing of the arteries that supply blood to the legs.
Choice B, sporadic ischemia, is wrong because it is not a specific medical term for a condition that causes leg pain.
Ischemia means reduced blood flow to a part of the body, which can cause pain, but it can be caused by various factors and affect different organs.
Choice C, angina, is wrong because it is a term for chest pain caused by reduced blood flow to the heart, not the legs.
Angina can also be triggered by physical activity and relieved by rest, but it is not related to PAD or leg ischemia.
Choice D, restless leg syndrome, is wrong because it is a condition that causes an uncomfortable urge to move the legs, usually at night or when lying down.
Restless leg syndrome does not cause pain or ischemia in the legs, and it is not improved by rest.It is thought to be related to a problem with the nervous system or iron deficiency.
Correct Answer is B
Explanation
Class IV antidysrhythmics or calcium channel blockers have the action ofdecreasing the flow of calcium ionsinto the cardiac and vascular smooth muscle cells, thusdecreasing heart rate and contractions.
This leads to vasodilation and myocardial depression, which can help control arrhythmias, hypertension and angina.
Choice A is wrong because calcium channel blockers do not increase blood vessel spasm, but rather relax them by inhibiting the calcium influx that causes contraction.
Choice C is wrong because calcium channel blockers do not promote platelet aggregation, but rather inhibit it by interfering with the calcium-dependent binding of fibrinogen to platelets.
Choice D is wrong because calcium channel blockers do not enhance sympathetic nervous system activity, but rather counteract it by reducing the cardiac output and peripheral resistance.
Some normal ranges for reference are:
• Heart rate: 60-100 beats per minute
• Blood pressure: 120/80 mmHg
• Calcium: 8.5-10.5 mg/dL
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