Which of the following Alpha adrenergic class has a vasodilating effect and can be used for the management of hypertension?
Alpha 3 adrenergic blocker.
Alpha 2 adrenergic antagonist.
Alpha 1 adrenergic agonist.
Alpha 1 Adrenergic Blocking Agents.
The Correct Answer is D
Alpha 1 adrenergic blocking agents have a vasodilating effect and can be used for the management of hypertension. They work by preventing the hormone norepinephrine from tightening the muscles in the walls of smaller arteries and veins, thus lowering the blood pressure. Some examples of alpha 1 blockers are doxazosin, prazosin, and terazosin.
Choice A is wrong because alpha 3 adrenergic blockers do not exist. There are only two subtypes of alpha receptors: alpha 1 and alpha 2.
Choice B is wrong because alpha 2 adrenergic antagonists are not used for hypertension. They are used for conditions like attention deficit hyperactivity disorder (ADHD) and opioid withdrawal. Alpha 2 antagonists block the negative feedback mechanism of norepinephrine release, thus increasing the amount of norepinephrine in the blood and raising the blood pressure.
Choice C is wrong because alpha 1 adrenergic agonists have the opposite effect of alpha 1 blockers. They stimulate the alpha 1 receptors and cause vasoconstriction, which increases the blood pressure. Alpha 1 agonists are used for conditions like nasal congestion and hypotension.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Dry mouth is a common adverse effect of anticholinergic agents used to treat overactive bladder syndrome (OAB).Anticholinergic agents prevent involuntary contractions of the bladder detrusor muscle by blocking the action of acetylcholine, a neurotransmitter that stimulates the muscle.However, anticholinergics are not tissue specific, and they also affect other parts of the body where acetylcholine is involved, such as the salivary glands, the gastrointestinal tract, and the eyes.
Choice B is wrong because restlessness is not a typical side effect of anticholinergic agents.In fact, anticholinergics can cause sedation and drowsiness in some people.
Choice C is wrong because increased salivation is the opposite of what anticholinergics do.Anticholinergics reduce the secretion of saliva, causing dry mouth.
Choice D is wrong because diarrhea is also the opposite of what anticholinergics do.Anticholinergics slow down the movement of the gastrointestinal tract, causing constipation.
Some other possible adverse effects of anticholinergic agents include blurred vision, urinary retention, confusion, memory impairment, and increased risk of dementia and mortality.
Therefore, these drugs should be used with caution and under medical supervision.
Correct Answer is C
Explanation
Phenazopyridine hydrochloride (Pyridium) is a urinary tract analgesic that can relieve the pain, burning, and discomfort caused by infection or irritation of the urinary tract.However, it can also cause some side effects, one of which is changing the color of bodily secretions to reddish orange. This is due to the excretion of the drug in the urine, saliva, sweat, and tears.The color change is harmless and usually disappears when the drug is stopped.
Choice A is wrong because phenazopyridine does not change bodily secretions to alkaline.In fact, it may interfere with the urine test that measures acidity (pH) and glucose.
Choice B is wrong because phenazopyridine does not change bodily secretions to pinkish.However, some other drugs, such as rifampin and doxorubicin, may cause urine to turn red or pink.
Choice D is wrong because phenazopyridine does not change bodily secretions to black.However, some other drugs, such as metronidazole and nitrofurantoin, may cause urine to turn brown or dark yellow.
Some other common side effects of phenazopyridine include headache, dizziness, indigestion, and stomach pain.Some serious side effects include skin itching, interference with the oxygen-carrying capacity of red blood cells, hemolytic anemia, and renal and hepatic toxicity.
These problems are more common in people who have existing kidney problems or take more than recommended.If you experience any of these symptoms, stop taking phenazopyridine hydrochloride and talk to a healthcare provider right away.
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