Which of the following Alpha adrenergic class has a vasodilating effect and can be used for the management of hypertension?
Alpha 3 adrenergic blocker.
Alpha 2 adrenergic antagonist.
Alpha 1 adrenergic agonist.
Alpha 1 Adrenergic Blocking Agents.
The Correct Answer is D
Alpha 1 adrenergic blocking agents have a vasodilating effect and can be used for the management of hypertension. They work by preventing the hormone norepinephrine from tightening the muscles in the walls of smaller arteries and veins, thus lowering the blood pressure. Some examples of alpha 1 blockers are doxazosin, prazosin, and terazosin.
Choice A is wrong because alpha 3 adrenergic blockers do not exist. There are only two subtypes of alpha receptors: alpha 1 and alpha 2.
Choice B is wrong because alpha 2 adrenergic antagonists are not used for hypertension. They are used for conditions like attention deficit hyperactivity disorder (ADHD) and opioid withdrawal. Alpha 2 antagonists block the negative feedback mechanism of norepinephrine release, thus increasing the amount of norepinephrine in the blood and raising the blood pressure.
Choice C is wrong because alpha 1 adrenergic agonists have the opposite effect of alpha 1 blockers. They stimulate the alpha 1 receptors and cause vasoconstriction, which increases the blood pressure. Alpha 1 agonists are used for conditions like nasal congestion and hypotension.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Angiotensin receptor blockers (ARBs) are a class of drugs that block the action of angiotensin II, a hormone that causes blood vessels to constrict and raise blood pressure. Examples of ARBs include losartan, valsartan, candesartan, and irbesartan.ARBs are used to treat hypertension, heart failure, and chronic kidney disease.
Choice A is wrong because calcium channel blockers (CCBs) are a class of drugs that prevent calcium from entering the cells of the heart and blood vessels, causing them to relax and lower blood pressure.
Examples of CCBs include amlodipine, diltiazem, verapamil, and nifedipine.CCBs are used to treat hypertension, angina, and arrhythmias.
Choice B is wrong because beta blockers are a class of drugs that reduce the heart rate and force of contraction, lowering the cardiac output and blood pressure.
Examples of beta blockers include atenolol, metoprolol, propranolol, and bisoprolol.Beta blockers are used to treat hypertension, angina, heart failure, and arrhythmias.
Choice C is wrong because platelet inhibitors are a class of drugs that prevent platelets from clumping together and forming blood clots.
Examples of platelet inhibitors include aspirin, clopidogrel, ticagrelor, and prasugrel.Platelet inhibitors are used to prevent or treat cardiovascular events such as heart attack or stroke.
Choice E is wrong because ACE inhibitors are a class of drugs that inhibit the enzyme that converts angiotensin I to angiotensin II, reducing the production of this vasoconstrictor hormone.
Examples of ACE inhibitors include lisinopril, enalapril, ramipril, and captopril.ACE inhibitors are used to treat hypertension, heart failure, and chronic kidney disease.
Correct Answer is C
Explanation
Phenazopyridine hydrochloride (Pyridium) is a urinary tract analgesic that can relieve the pain, burning, and discomfort caused by infection or irritation of the urinary tract.However, it can also cause some side effects, one of which is changing the color of bodily secretions to reddish orange. This is due to the excretion of the drug in the urine, saliva, sweat, and tears.The color change is harmless and usually disappears when the drug is stopped.
Choice A is wrong because phenazopyridine does not change bodily secretions to alkaline.In fact, it may interfere with the urine test that measures acidity (pH) and glucose.
Choice B is wrong because phenazopyridine does not change bodily secretions to pinkish.However, some other drugs, such as rifampin and doxorubicin, may cause urine to turn red or pink.
Choice D is wrong because phenazopyridine does not change bodily secretions to black.However, some other drugs, such as metronidazole and nitrofurantoin, may cause urine to turn brown or dark yellow.
Some other common side effects of phenazopyridine include headache, dizziness, indigestion, and stomach pain.Some serious side effects include skin itching, interference with the oxygen-carrying capacity of red blood cells, hemolytic anemia, and renal and hepatic toxicity.
These problems are more common in people who have existing kidney problems or take more than recommended.If you experience any of these symptoms, stop taking phenazopyridine hydrochloride and talk to a healthcare provider right away.
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