The antagonistic agent to digoxin toxicity is what?
Protamine sulfate.
Acetylcysteine.
Antidigoxin.
Activated charcoal.
The Correct Answer is C
Antidigoxin is an antidote for digoxin toxicity that binds and inactivates digoxin, a cardiac glycoside that can cause life-threatening arrhythmias, hyperkalemia, and other symptoms when overdosed. Antidigoxin is also known as digoxin immune Fab or DIGIFab.
Choice A, protamine sulfate, is wrong because it is an antidote for heparin, an anticoagulant that can cause bleeding when overdosed.
Choice B, acetylcysteine, is wrong because it is an antidote for acetaminophen, a painkiller that can cause liver damage when overdosed.
Choice D, activated charcoal, is wrong because it is a nonspecific adsorbent that can reduce the absorption of some drugs or poisons from the gastrointestinal tract, but it is not effective for digoxin toxicity.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
HDL stands for high-density lipoprotein, which is a type of cholesterol that carries excess cholesterol from other parts of the body to the liver, where it can be removed.
HDL is sometimes called “good” cholesterol because it helps protect against heart disease.Having high HDL levels is not a characteristic of metabolic syndrome, but rather a protective factor.
Metabolic syndrome is a group of conditions that increase the risk of heart disease, stroke, and type 2 diabetes.These conditions include:
• Low HDLs (choice A): Having low levels of HDL cholesterol is a risk factor for metabolic syndrome, as it means there is less “good” cholesterol to remove excess cholesterol from the blood vessels.
• Type II diabetes mellitus (choice B): This is a condition where the body does not use insulin properly, leading to high blood sugar levels.
Insulin is a hormone that helps the cells take up glucose from the blood.
Insulin resistance is a key feature of metabolic syndrome.
• Hypertension (choice C): This means having high blood pressure, which can damage the heart and blood vessels over time.
High blood pressure is often associated with obesity and insulin resistance, which are common in metabolic syndrome.
• Abdominal obesity (choice E): This means having excess fat around the waist and trunk, also known as central or visceral obesity.
This type of fat is more harmful than fat in other parts of the body, as it can release inflammatory substances that affect the metabolism and increase the risk of cardiovascular disease.
• Hyperglycemia (choice F): This means having high blood sugar levels, which can damage the blood vessels and organs over time.
Hyperglycemia can result from insulin resistance or type 2 diabetes, which are both components of metabolic syndrome.
The normal ranges for some of these conditions are:
• HDL cholesterol: more than 40 mg/dL for men and more than 50 mg/dL for women
• Blood pressure: less than 120/80 mmHg
• Blood sugar: less than 100 mg/dL after fasting or less than 140 mg/dL two hours after eating
• Waist circumference: less than 40 inches for men and less than 35 inches for women
Correct Answer is A
Explanation
Intermittent claudication is a condition in which leg pain is produced upon increased activity and ischemia to tissues, but then the pain is reduced with rest. This is because the blood flow to the leg muscles is insufficient to meet the increased demand during exercise, but adequate at rest.Intermittent claudication is a common symptom of peripheral artery disease (PAD), which is a narrowing of the arteries that supply blood to the legs.
Choice B, sporadic ischemia, is wrong because it is not a specific medical term for a condition that causes leg pain.
Ischemia means reduced blood flow to a part of the body, which can cause pain, but it can be caused by various factors and affect different organs.
Choice C, angina, is wrong because it is a term for chest pain caused by reduced blood flow to the heart, not the legs.
Angina can also be triggered by physical activity and relieved by rest, but it is not related to PAD or leg ischemia.
Choice D, restless leg syndrome, is wrong because it is a condition that causes an uncomfortable urge to move the legs, usually at night or when lying down.
Restless leg syndrome does not cause pain or ischemia in the legs, and it is not improved by rest.It is thought to be related to a problem with the nervous system or iron deficiency.
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