A client is prescribed a thiazide diuretic for the management of hypertension.
The nurse plans to assess the client for allergy to?

Digibind is the trade name forantidigoxin, which is an antibody made up of anti-digoxin immunoglobulin fragments.It is thespecific antidoteto digoxin toxicity, which can occur even when the serum digoxin concentration is within the therapeutic range.Digoxin toxicity causes anorexia, nausea, vomiting, neurological symptoms and arrhythmias.

Choice A, Protamine sulfate, is wrong because it is the antidote for heparin overdose, not digoxin toxicity.

Protamine sulfate reverses the anticoagulant effect of heparin by binding to it and forming a stable complex.

Choice B, Acetylcysteine, is wrong because it is the antidote for acetaminophen overdose, not digoxin toxicity.

Acetylcysteine replenishes glutathione, which is depleted by acetaminophen metabolites that cause hepatotoxicity.

Choice D, Vitamin K, is wrong because it is the antidote for warfarin overdose, not digoxin toxicity.

Vitamin K restores the synthesis of clotting factors that are inhibited by warfarin.

Normal ranges for serum digoxin concentration are 0.6 to 1.2 nanomol/L (0.5 to 0.9 nanograms/mL) for heart failure and unknown for atrial fibrillation without heart failure.

Normal ranges for serum potassium level are 3.5 to 5.0 mmol/L and for serum magnesium level are 0.7 to 1.0 mmol/L.

Atorvastatin is a type ofstatin, which are the most potent antilipidemic agents, and have proven to lower the risk of myocardial infarction by reducing the levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the blood.Statins also slightly increase the level of high-density lipoprotein (HDL) cholesterol, which is beneficial for cardiovascular health.

Choice B, niacin, is a type ofnicotinic acid, which can lower LDL cholesterol and triglycerides, and increase HDL cholesterol, but it is less effective than statins and has more side effects, such as flushing, itching, and liver toxicity.

Choice C, gemfibrozil, is a type offibric acid derivative, which can lower triglycerides and increase HDL cholesterol, but have little effect on LDL cholesterol.They are mainly used for patients with high triglyceride levels or low HDL cholesterol levels.

Choice D, amlodipine, is not an antilipidemic agent at all.It is a type ofcalcium channel blocker, which is used to treat hypertension and angina by relaxing the blood vessels and reducing the workload of the heart.