A nurse in a provider's office is monitoring blood electrolytes for four clients who take digoxin.
Which of the following electrolyte values increases a client's risk for digoxin toxicity?
Potassium 3.0 mEq/L.
Calcium 9.2 mg/dL.
Sodium 140 mEq/L.
Magnesium 2.2 mg/dL.
The Correct Answer is A
This is because low potassium levels (hypokalemia) increase the sensitivity of the heart to digoxin and can lead to toxicity even with normal serum digoxin levels. Digoxin inhibits the sodium-potassium pump on the cardiac cells, which causes potassium to accumulate outside the cells. Low potassium levels in the blood create a larger gradient for potassium to move out of the cells, which enhances the effect of digoxin and can cause arrhythmias.
Choice B is wrong because calcium 9.2 mg/dL is within the normal range (8.5 to 10.2 mg/dL) and does not increase the risk of digoxin toxicity. However, high calcium levels (hypercalcemia) can potentiate the effects of digoxin and cause toxicity.
Choice C is wrong because sodium 140 mEq/L is within the normal range (135 to 145 mEq/L) and does not increase the risk of digoxin toxicity. However, high sodium levels (hypernatremia) can reduce the binding of digoxin to the sodium-potassium pump and decrease its efficacy.
Choice D is wrong because magnesium 2.2 mg/dL is within the normal range (1.7 to 2.4 mg/dL) and does not increase the risk of digoxin toxicity. However, low magnesium levels (hypomagnesemia) can increase the sensitivity of the heart to digoxin and cause toxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
This range of systolic blood pressure is classified as stage 1 hypertension according to the American College of Cardiology and the American Heart Association. Stage 1 hypertension is when blood pressure consistently ranges from 130 to 139 systolic or 80 to 89 mm Hg diastolic.At this stage of high blood pressure, health care professionals are likely to prescribe lifestyle changes and may consider adding blood pressure medication based on your risk of atherosclerotic cardiovascular disease, or ASCVD, such as heart attack or stroke.
Choice A is wrong because 140 to 159 is the range for stage 2 hypertension, which is more severe than stage 1.
Stage 2 hypertension is when blood pressure consistently is 140/90 mm Hg or higher.At this stage of high blood pressure, health care professionals are likely to prescribe a combination of blood pressure medications and lifestyle changes.
Choice C is wrong because 110 to 119 is the range for normal blood pressure.
Normal blood pressure is when systolic blood pressure is less than 120 mm Hg and diastolic blood pressure is less than 80 mm Hg.If your results fall into this category, stick with heart-healthy habits like following a balanced diet and getting regular exercise.
Choice D is wrong because 120 to 139 is not a valid range for systolic blood pressure.
It includes two different categories: elevated and stage 1 hypertension.
Elevated blood pressure is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.People with elevated blood pressure are likely to develop high blood pressure unless steps are taken to control the condition.Stage 1 hypertension, as explained above, is when systolic blood pressure ranges from 130 to 139 or diastolic blood pressure ranges from 80 to 89.
The normal range for systolic blood pressure is less than 120 mm Hg.The normal range for diastolic blood pressure is less than 80 mm Hg.
Correct Answer is C
Explanation
Positive inotropy and negative chronotropy.Digoxin is a cardiac glycoside that increases the force of the heart contractions (positive inotropy) and slows down the heart rate (negative chronotropy).
Choice A is wrong because positive chronotropy means increasing the heart rate, which is the opposite of what digoxin does.
Choice B is wrong because negative inotropy means decreasing the force of the heart contractions, which is also the opposite of what digoxin does.
Choice D is wrong because positive chronotropy means increasing the heart rate, which is not what digoxin does.
Digoxin is used to treat heart failure and atrial fibrillation, a type of irregular heartbeat.It has a narrow therapeutic window, meaning that the dose must be carefully adjusted to avoid toxicity or ineffectiveness.
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