A patient with peripheral vascular disease has been on pentoxifylline (Trental) for 2 weeks.
Which statements by the patient indicate no need for further patient teaching about the disease? Select all that apply.
"I should quit smoking to improve blood flow.".
"I need to avoid prolonged sitting or standing.".
"I should take my pentoxifylline with meals.".
"I need to limit my physical activity to avoid worsening symptoms.".
Correct Answer : A,B
Pentoxifylline is a medication that improves blood flow and oxygen delivery to the tissues in patients with peripheral vascular disease (PVD), a condition that causes narrowing of the arteries in the legs. Pentoxifylline can help reduce the symptoms of intermittent claudication, which is cramping pain in the legs that occurs with walking and improves with rest.
Choice A is correct because smoking is a major risk factor for PVD and quitting smoking can improve blood flow and prevent further damage to the arteries.
Choice B is correct because prolonged sitting or standing can reduce blood flow to the legs and worsen symptoms of PVD.
Patients should avoid crossing their legs, wearing tight clothing, or exposing their legs to cold temperatures. They should also elevate their legs when resting and move them frequently.
Choice C is wrong because pentoxifylline should be taken on an empty stomach, at least one hour before or two hours after meals, to increase its absorption and effectiveness.
Choice D is wrong because physical activity is beneficial for patients with PVD and intermittent claudication.
Exercise can improve blood circulation, increase muscle strength, reduce pain, and lower cardiovascular risk factors. Patients should be encouraged to walk regularly, as tolerated, and follow a supervised exercise program if available.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Anticoagulants are medicines that increase the time it takes for blood to clot.They do not dissolve existing clots, but they can stop them from getting bigger or prevent new clots from forming.Anticoagulants work by interfering with different steps of the blood coagulation pathway, which is a complex process that involves many clotting factors.
Choice A is wrong because anticoagulants do not dissolve existing clots.To dissolve clots, you need medicines called thrombolytics or fibrinolytics, which break down the fibrin that holds the clots together.
Choice B is wrong because anticoagulants do not transport platelets.
Platelets are blood cells that help with clotting by sticking together and forming a plug at the site of an injury.Anticoagulants may affect the function of platelets, but they do not move them around.
Choice D is wrong because anticoagulants do not increase blood viscosity.
Viscosity is a measure of how thick and sticky a fluid is.
Anticoagulants are sometimes called blood thinners, but they do not actually change the viscosity of blood.They just make it less likely to clot.
Normal ranges for blood clotting tests vary depending on the type of test and the laboratory that performs it.
Some common tests and their normal ranges are:
• Prothrombin time (PT): 11 to 13.5 seconds
• International normalized ratio (INR): 0.8 to 1.2
• Activated partial thromboplastin time (aPTT): 25 to 35 seconds
• Anti-factor Xa: 0.3 to 0.7 units/mL
• D-dimer: less than 0.5 mcg/mL
Correct Answer is B
Explanation
PT stands for prothrombin time, which is a measure of how long it takes the blood to clot.
INR stands for international normalized ratio, which is a way of standardizing the PT results across different laboratories.
Warfarin is a blood thinner that works by inhibiting the production of vitamin K-dependent clotting factors in the liver.
Therefore, warfarin prolongs the PT and increases the INR.The PT/INR test is used to monitor the effectiveness of warfarin therapy and adjust the dose accordingly.
Choice A is wrong because PTT stands for partial thromboplastin time, which is another measure of blood clotting time, but it reflects the activity of different clotting factors than PT.PTT is used to monitor heparin therapy, not warfarin therapy.
Choice C is wrong because aPTT stands for activated partial thromboplastin time, which is a variation of PTT that uses an activator to speed up the clotting time.Like PTT, aPTT is used to monitor heparin therapy, not warfarin therapy.
Choice D is wrong because ACT stands for activated clotting time, which is a measure of the whole blood clotting time.ACT is used to monitor high-dose heparin therapy during certain procedures, such as cardiac bypass surgery or angioplasty.
The normal ranges for these tests may vary depending on the laboratory and the method used, but generally, they are:
• PT: 10 to 13 seconds
• INR: 0.8 to 1.2 (without warfarin) or 2.0 to 3.0 (with warfarin)
• PTT: 25 to 35 seconds
• aPTT: 30 to 40 seconds
• ACT: 70 to 120 seconds
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