Which administration strategy can a patient implement to reduce flushing, the most common adverse effect of niacin therapy?
Take before starting daily activities.
Take with a sedative.
Take with grapefruit juice.
Take with an NSAID such as ibuprofen.
The Correct Answer is D
Taking niacin with an NSAID such as ibuprofen can reduce flushing, the most common adverse effect of niacin therapy. Flushing is a side effect of taking large doses of niacin (vitamin B3) supplements. It happens when the niacin causes the small blood vessels in your skin to dilate so more blood can rush through. Flushing can cause skin redness, warmth, itching, tingling, or burning sensations.
Choice A is wrong because taking niacin before starting daily activities can increase the risk of flushing and interfere with your routine. Flushing usually occurs within 15 to 30 minutes of taking niacin and lasts for about an hour.
Choice B is wrong because taking niacin with a sedative can increase the risk of liver damage, especially if the sedative is acetaminophen (Tylenol). Niacin can also cause liver problems at high doses, so combining it with another liver-toxic drug is not advisable.
Choice C is wrong because taking niacin with grapefruit juice can increase the risk of side effects, such as low blood pressure, dizziness, or fainting. Grapefruit juice can interfere with the metabolism of some drugs, including niacin, and make them more potent or toxic.
Normal ranges for niacin intake vary depending on age and gender. The recommended dietary allowance (RDA) for adult males is 16 mg per day and for adult females is 14 mg per day. Higher doses of niacin may be prescribed by a doctor to treat high cholesterol or other conditions, but they should be taken under medical supervision and with caution.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B"]
Explanation
This is a mnemonic to remember the common suffix of drugs that block the beta receptors in the heart and blood vessels, which can lower blood pressure, heart rate, and reduce chest pain. For example, metoprolol, atenolol, and propranolol are beta blockers.
Choice A is wrong because calcium channel blockers do not end in DIPINE.
Calcium channel blockers are drugs that block the entry of calcium into the cells of the heart and blood vessels, which can relax the blood vessels and lower blood pressure.
Some calcium channel blockers end in DIPINE, such as amlodipine and nifedipine, but not all of them.
For example, verapamil and diltiazem are also calcium channel blockers.
Choice C is wrong because ACE inhibitors do not end in ZoSIN.
ACE inhibitors are drugs that inhibit the enzyme angiotensin-converting enzyme (ACE), which can lower blood pressure and prevent heart failure.
ACE inhibitors usually end in PRIL, such as lisinopril, enalapril, and captopril.
Choice D is wrong because angiotensin II receptor blockers do not end in STATIN.
Angiotensin II receptor blockers are drugs that block the action of angiotensin II, a hormone that constricts blood vessels and raises blood pressure.
Angiotensin II receptor blockers usually end in SARTAN, such as losartan, valsartan, and irbesartan.
The normal range for blood pressure is less than 120/80 mmHg.
The normal range for heart rate is 60 to 100 beats per minute.
Correct Answer is B
Explanation
This range of systolic blood pressure is classified as stage 1 hypertension according to the American College of Cardiology and the American Heart Association. Stage 1 hypertension is when blood pressure consistently ranges from 130 to 139 systolic or 80 to 89 mm Hg diastolic.At this stage of high blood pressure, health care professionals are likely to prescribe lifestyle changes and may consider adding blood pressure medication based on your risk of atherosclerotic cardiovascular disease, or ASCVD, such as heart attack or stroke.
Choice A is wrong because 140 to 159 is the range for stage 2 hypertension, which is more severe than stage 1.
Stage 2 hypertension is when blood pressure consistently is 140/90 mm Hg or higher.At this stage of high blood pressure, health care professionals are likely to prescribe a combination of blood pressure medications and lifestyle changes.
Choice C is wrong because 110 to 119 is the range for normal blood pressure.
Normal blood pressure is when systolic blood pressure is less than 120 mm Hg and diastolic blood pressure is less than 80 mm Hg.If your results fall into this category, stick with heart-healthy habits like following a balanced diet and getting regular exercise.
Choice D is wrong because 120 to 139 is not a valid range for systolic blood pressure.
It includes two different categories: elevated and stage 1 hypertension.
Elevated blood pressure is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.People with elevated blood pressure are likely to develop high blood pressure unless steps are taken to control the condition.Stage 1 hypertension, as explained above, is when systolic blood pressure ranges from 130 to 139 or diastolic blood pressure ranges from 80 to 89.
The normal range for systolic blood pressure is less than 120 mm Hg.The normal range for diastolic blood pressure is less than 80 mm Hg.
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