Patients taking which cholesterol-lowering agent may require supplements of fat-soluble vitamins A, D, E, and K?
Nicotinic acid.
Nitroglycerin.
Bile acid-binding resins.
Beta Blockers.
The Correct Answer is C
Bile acid-binding resins are cholesterol-lowering agents that bind to bile acids in the intestine and prevent their reabsorption. This reduces the amount of bile acids available for cholesterol synthesis in the liver, which lowers the levels of LDL cholesterol in the blood. However, bile acids are also needed for the absorption of fat-soluble vitamins A, D, E, and K. Therefore, patients taking bile acid-binding resins may require supplements of these vitamins to prevent deficiency.
Choice A is wrong because nicotinic acid, or niacin, is a B vitamin that can lower cholesterol by limiting the production of fats in the liver. It does not affect the absorption of fat-soluble vitamins.
Choice B is wrong because nitroglycerin is not a cholesterol-lowering agent, but a vasodilator that relaxes the blood vessels and improves blood flow. It has no effect on fat-soluble vitamin absorption.
Choice D is wrong because beta blockers are not cholesterol-lowering agents, but drugs that lower blood pressure and heart rate by blocking the effects of adrenaline. They have no effect on fat-soluble vitamin absorption.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
This is because potassium sparing diuretics do not lower potassium levels in the blood, unlike other types of diuretics.Potassium is an essential electrolyte that serves nerve and muscular functions and is regulated by the kidneys.Low potassium levels can cause irregular heartbeats and other problems. Therefore, patients taking potassium sparing diuretics should avoid food sources that are high in potassium, such as bananas, avocados, spinach, and potatoes.
Choice A is wrong because thiazide diuretics, such as hydrochlorothiazide, can cause low potassium levels in the blood.
Patients taking thiazide diuretics may need to take potassium supplements or eat more potassium-rich foods to prevent hypokalemia.
Choice B is wrong because osmotic diuretics, such as mannitol, do not affect potassium levels in the blood.
They work by increasing the amount of water in the urine, but do not alter the electrolyte balance.
Osmotic diuretics are mainly used to treat cerebral edema and glaucoma.
Choice D is wrong because loop diuretics, such as furosemide, can also cause low potassium levels in the blood.
They work by inhibiting the reabsorption of sodium and water in the loop of Henle, a part of the kidney.
Loop diuretics are used to treat edema and heart failure.
Normal ranges for potassium in the blood are 3.5 to 5.0 millimoles per liter (mmol/L).
Correct Answer is B
Explanation
Class IV antidysrhythmics or calcium channel blockers have the action ofdecreasing the flow of calcium ionsinto the cardiac and vascular smooth muscle cells, thusdecreasing heart rate and contractions.
This leads to vasodilation and myocardial depression, which can help control arrhythmias, hypertension and angina.
Choice A is wrong because calcium channel blockers do not increase blood vessel spasm, but rather relax them by inhibiting the calcium influx that causes contraction.
Choice C is wrong because calcium channel blockers do not promote platelet aggregation, but rather inhibit it by interfering with the calcium-dependent binding of fibrinogen to platelets.
Choice D is wrong because calcium channel blockers do not enhance sympathetic nervous system activity, but rather counteract it by reducing the cardiac output and peripheral resistance.
Some normal ranges for reference are:
• Heart rate: 60-100 beats per minute
• Blood pressure: 120/80 mmHg
• Calcium: 8.5-10.5 mg/dL
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