Match the following drug classification with the appropriate drug,
Calcium channel blockers:.
Beta Blocker:.
Platelet inhibitors:.
Angiotensin receptor blocker (ARBS):.
ACE inhibitor:.
The Correct Answer is D
Angiotensin receptor blockers (ARBs) are a class of drugs that block the action of angiotensin II, a hormone that causes blood vessels to constrict and raise blood pressure. Examples of ARBs include losartan, valsartan, candesartan, and irbesartan. ARBs are used to treat hypertension, heart failure, and chronic kidney disease.
Choice A is wrong because calcium channel blockers (CCBs) are a class of drugs that prevent calcium from entering the cells of the heart and blood vessels, causing them to relax and lower blood pressure.
Examples of CCBs include amlodipine, diltiazem, verapamil, and nifedipine. CCBs are used to treat hypertension, angina, and arrhythmias.
Choice B is wrong because beta blockers are a class of drugs that reduce the heart rate and force of contraction, lowering the cardiac output and blood pressure.
Examples of beta blockers include atenolol, metoprolol, propranolol, and bisoprolol. Beta blockers are used to treat hypertension, angina, heart failure, and arrhythmias.
Choice C is wrong because platelet inhibitors are a class of drugs that prevent platelets from clumping together and forming blood clots.
Examples of platelet inhibitors include aspirin, clopidogrel, ticagrelor, and prasugrel. Platelet inhibitors are used to prevent or treat cardiovascular events such as heart attack or stroke.
Choice E is wrong because ACE inhibitors are a class of drugs that inhibit the enzyme that converts angiotensin I to angiotensin II, reducing the production of this vasoconstrictor hormone.
Examples of ACE inhibitors include lisinopril, enalapril, ramipril, and captopril. ACE inhibitors are used to treat hypertension, heart failure, and chronic kidney disease.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Positive inotropy and negative chronotropy.Digoxin is a cardiac glycoside that increases the force of the heart contractions (positive inotropy) and slows down the heart rate (negative chronotropy).
Choice A is wrong because positive chronotropy means increasing the heart rate, which is the opposite of what digoxin does.
Choice B is wrong because negative inotropy means decreasing the force of the heart contractions, which is also the opposite of what digoxin does.
Choice D is wrong because positive chronotropy means increasing the heart rate, which is not what digoxin does.
Digoxin is used to treat heart failure and atrial fibrillation, a type of irregular heartbeat.It has a narrow therapeutic window, meaning that the dose must be carefully adjusted to avoid toxicity or ineffectiveness.
Correct Answer is A
Explanation
Atorvastatin is a type of statin, which are the most potent antilipidemic agents and have proven to lower the risk of myocardial infarction. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is involved in the synthesis of cholesterol in the liver.By reducing the production of cholesterol, statins lower the levels of low-density lipoprotein (LDL) and triglycerides, and slightly increase the levels of high-density lipoprotein (HDL) in the blood.
Choice B, niacin, is wrong because niacin is not as effective as statins in lowering LDL and preventing cardiovascular events.Niacin is a water-soluble vitamin that can lower LDL and triglycerides, and increase HDL, but it can also cause flushing, itching, and liver toxicity.
Choice C, gemfibrozil, is wrong because gemfibrozil is a type of fibric acid derivative, which are mainly used to lower triglycerides and increase HDL, but have little effect on LDL.
Fibric acid derivatives work by activating a receptor called PPAR-alpha, which regulates the metabolism of lipids in the liver and muscle.Fibric acid derivatives can also increase the risk of gallstones and muscle damage.
Choice D, ezetimibe, is wrong because ezetimibe is a selective cholesterol absorption inhibitor, which blocks the absorption of dietary and biliary cholesterol in the intestine.Ezetimibe can lower LDL by about 15-20%, but it has not been shown to reduce the risk of myocardial infarction on its own.Ezetimibe is usually combined with a statin for better efficacy and safety.
Normal ranges for lipid levels are:
• Total cholesterol: less than 200 mg/dL
• LDL cholesterol: less than 100 mg/dL
• HDL cholesterol: more than 40 mg/dL for men and more than 50 mg/dL for women
• Triglycerides: less than 150 mg/dL
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