Up to one-third of patients who take ACE inhibitors for hypertension report which symptom after beginning therapy?

Decreased white blood cells.

Swelling of the face and lips.

Chronic cough.

Renal failure.

Answer and Explanation

The Correct Answer is C

ACE inhibitors are a type of medication used to treat high blood pressure and heart failure. They work by blocking the production of a hormone called angiotensin II, which narrows the blood vessels and increases blood pressure. By preventing this hormone from acting, ACE inhibitors lower blood pressure and reduce the workload on the heart. One of the most common side effects of ACE inhibitors is a dry cough, which occurs in 12–19% of people who take them. The cough is caused by the accumulation of a substance called bradykinin, which is normally broken down by angiotensin-converting enzyme (ACE). When ACE is inhibited, bradykinin levels increase and cause irritation and inflammation in the airways.

Choice A is wrong because decreased white blood cells are not a common side effect of ACE inhibitors.

However, some people may develop a condition called neutropenia, which is a low level of a type of white blood cell called neutrophils. This can increase the risk of infections and may require stopping the medication.

Choice B is wrong because swelling of the face and lips is not a common side effect of ACE inhibitors.

However, some people may develop a rare but serious allergic reaction called angioedema, which is a swelling of the deeper layers of the skin and mucous membranes.

This can affect the face, lips, tongue, throat, or other parts of the body and can cause difficulty breathing or swallowing. Angioedema can be life-threatening and requires immediate medical attention.

Choice D is wrong because renal failure is not a common side effect of ACE inhibitors.

However, some people may experience a decrease in kidney function or an increase in blood levels of creatinine, which is a waste product filtered by the kidneys.

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Correct Answer is A

Explanation

Atorvastatin is a type ofstatin, which are the most potent antilipidemic agents, and have proven to lower the risk of myocardial infarction by reducing the levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the blood.Statins also slightly increase the level of high-density lipoprotein (HDL) cholesterol, which is beneficial for cardiovascular health.

Choice B, niacin, is a type ofnicotinic acid, which can lower LDL cholesterol and triglycerides, and increase HDL cholesterol, but it is less effective than statins and has more side effects, such as flushing, itching, and liver toxicity.

Choice C, gemfibrozil, is a type offibric acid derivative, which can lower triglycerides and increase HDL cholesterol, but have little effect on LDL cholesterol.They are mainly used for patients with high triglyceride levels or low HDL cholesterol levels.

Choice D, amlodipine, is not an antilipidemic agent at all.It is a type ofcalcium channel blocker, which is used to treat hypertension and angina by relaxing the blood vessels and reducing the workload of the heart.

A. Apply a new patch every 48hr. B. Cut each patch in half if angina attacks are under control. C. Take off the nitroglycerin patch for 30 min if a headache occurs. D. Remove the patch each evening.

Correct Answer is D

Explanation

This is because nitroglycerin patches can cause tolerance if they are used continuously, which reduces their effectiveness in preventing angina attacks. Removing the patch each evening allows the body to restore its sensitivity to the drug.

Choice A is wrong because nitroglycerin patches should be applied every 24 hours, not every 48 hours.

Applying a new patch every 48 hours would result in inadequate blood levels of the drug and increased risk of angina.

Choice B is wrong because nitroglycerin patches should not be cut in half or altered in any way.

Cutting the patch would compromise the integrity of the drug delivery system and could lead to unpredictable or excessive doses of the drug.

Choice C is wrong because nitroglycerin patches should not be taken off for 30 minutes if a headache occurs.

Headache is a common side effect of nitroglycerin due to its vasodilating action, but it usually subsides with continued use.

Taking off the patch for 30 minutes could increase the risk of angina by interrupting the steady blood levels of the drug.

The nurse should advise the client to take an analgesic such as acetaminophen for headache relief.

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Up to one-third of patients who take ACE inhibitors for hypertension report which symptom after beginning therapy?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following anti-lipidemic drugs are the most potent antilipidemic agents, and have proven to lower the risk of Myocardial Infarction?

Correct Answer is A

Explanation

A nurse is reinforcing teaching with a client who has a new prescription for nitroglycerin transdermal patch for angina pectoris. Which of the following instructions should the nurse include?

Correct Answer is D

Explanation

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