Up to one-third of patients who take ACE inhibitors for hypertension report which symptom after beginning therapy?
Decreased white blood cells.
Swelling of the face and lips.
Chronic cough.
Renal failure.
The Correct Answer is C
ACE inhibitors are a type of medication used to treat high blood pressure and heart failure. They work by blocking the production of a hormone called angiotensin II, which narrows the blood vessels and increases blood pressure. By preventing this hormone from acting, ACE inhibitors lower blood pressure and reduce the workload on the heart. One of the most common side effects of ACE inhibitors is a dry cough, which occurs in 12–19% of people who take them. The cough is caused by the accumulation of a substance called bradykinin, which is normally broken down by angiotensin-converting enzyme (ACE). When ACE is inhibited, bradykinin levels increase and cause irritation and inflammation in the airways.
Choice A is wrong because decreased white blood cells are not a common side effect of ACE inhibitors.
However, some people may develop a condition called neutropenia, which is a low level of a type of white blood cell called neutrophils. This can increase the risk of infections and may require stopping the medication.
Choice B is wrong because swelling of the face and lips is not a common side effect of ACE inhibitors.
However, some people may develop a rare but serious allergic reaction called angioedema, which is a swelling of the deeper layers of the skin and mucous membranes.
This can affect the face, lips, tongue, throat, or other parts of the body and can cause difficulty breathing or swallowing. Angioedema can be life-threatening and requires immediate medical attention.
Choice D is wrong because renal failure is not a common side effect of ACE inhibitors.
However, some people may experience a decrease in kidney function or an increase in blood levels of creatinine, which is a waste product filtered by the kidneys.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B"]
Explanation
This is a mnemonic to remember the common suffix of drugs that block the beta receptors in the heart and blood vessels, which can lower blood pressure, heart rate, and reduce chest pain. For example, metoprolol, atenolol, and propranolol are beta blockers.
Choice A is wrong because calcium channel blockers do not end in DIPINE.
Calcium channel blockers are drugs that block the entry of calcium into the cells of the heart and blood vessels, which can relax the blood vessels and lower blood pressure.
Some calcium channel blockers end in DIPINE, such as amlodipine and nifedipine, but not all of them.
For example, verapamil and diltiazem are also calcium channel blockers.
Choice C is wrong because ACE inhibitors do not end in ZoSIN.
ACE inhibitors are drugs that inhibit the enzyme angiotensin-converting enzyme (ACE), which can lower blood pressure and prevent heart failure.
ACE inhibitors usually end in PRIL, such as lisinopril, enalapril, and captopril.
Choice D is wrong because angiotensin II receptor blockers do not end in STATIN.
Angiotensin II receptor blockers are drugs that block the action of angiotensin II, a hormone that constricts blood vessels and raises blood pressure.
Angiotensin II receptor blockers usually end in SARTAN, such as losartan, valsartan, and irbesartan.
The normal range for blood pressure is less than 120/80 mmHg.
The normal range for heart rate is 60 to 100 beats per minute.
Correct Answer is B
Explanation
PT stands for prothrombin time, which is a measure of how long it takes the blood to clot.
INR stands for international normalized ratio, which is a way of standardizing the PT results across different laboratories.
Warfarin is a blood thinner that works by inhibiting the production of vitamin K-dependent clotting factors in the liver.
Therefore, warfarin prolongs the PT and increases the INR.The PT/INR test is used to monitor the effectiveness of warfarin therapy and adjust the dose accordingly.
Choice A is wrong because PTT stands for partial thromboplastin time, which is another measure of blood clotting time, but it reflects the activity of different clotting factors than PT.PTT is used to monitor heparin therapy, not warfarin therapy.
Choice C is wrong because aPTT stands for activated partial thromboplastin time, which is a variation of PTT that uses an activator to speed up the clotting time.Like PTT, aPTT is used to monitor heparin therapy, not warfarin therapy.
Choice D is wrong because ACT stands for activated clotting time, which is a measure of the whole blood clotting time.ACT is used to monitor high-dose heparin therapy during certain procedures, such as cardiac bypass surgery or angioplasty.
The normal ranges for these tests may vary depending on the laboratory and the method used, but generally, they are:
• PT: 10 to 13 seconds
• INR: 0.8 to 1.2 (without warfarin) or 2.0 to 3.0 (with warfarin)
• PTT: 25 to 35 seconds
• aPTT: 30 to 40 seconds
• ACT: 70 to 120 seconds
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