Up to one-third of patients who take ACE inhibitors for hypertension report which symptom after beginning therapy?
Decreased white blood cells.
Swelling of the face and lips.
Chronic cough.
Renal failure.
The Correct Answer is C
ACE inhibitors are a type of medication used to treat high blood pressure and heart failure. They work by blocking the production of a hormone called angiotensin II, which narrows the blood vessels and increases blood pressure. By preventing this hormone from acting, ACE inhibitors lower blood pressure and reduce the workload on the heart. One of the most common side effects of ACE inhibitors is a dry cough, which occurs in 12–19% of people who take them. The cough is caused by the accumulation of a substance called bradykinin, which is normally broken down by angiotensin-converting enzyme (ACE). When ACE is inhibited, bradykinin levels increase and cause irritation and inflammation in the airways.
Choice A is wrong because decreased white blood cells are not a common side effect of ACE inhibitors.
However, some people may develop a condition called neutropenia, which is a low level of a type of white blood cell called neutrophils. This can increase the risk of infections and may require stopping the medication.
Choice B is wrong because swelling of the face and lips is not a common side effect of ACE inhibitors.
However, some people may develop a rare but serious allergic reaction called angioedema, which is a swelling of the deeper layers of the skin and mucous membranes.
This can affect the face, lips, tongue, throat, or other parts of the body and can cause difficulty breathing or swallowing. Angioedema can be life-threatening and requires immediate medical attention.
Choice D is wrong because renal failure is not a common side effect of ACE inhibitors.
However, some people may experience a decrease in kidney function or an increase in blood levels of creatinine, which is a waste product filtered by the kidneys.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Class IV antidysrhythmics or calcium channel blockers decrease the flow of calcium ions into cardiac and vascular smooth muscle cells, thus decreasing heart rate and contractions.By reducing the calcium influx, they also decrease the slope of phase 0 and 4 and prolong phase 2 of the cardiac action potential.This results in vasodilation, reduced myocardial oxygen demand, and decreased conduction through the AV node.
Choice A is wrong because calcium channel blockers do not increase blood vessel spasm, but rather cause vasodilation.
Choice C is wrong because calcium channel blockers do not decrease refractory period, but rather prolong it by extending phase 2 of the cardiac action potential.
Choice D is wrong because calcium channel blockers do not increase heart rate, but rather decrease it by slowing down the pacemaker activity and AV nodal conduction.
Normal ranges for heart rate are 60 to 100 beats per minute, and for blood pressure are 120/80 mmHg or lower.
Correct Answer is D
Explanation
Diuretics are medicines that help the kidneys get rid of excess water and salt, which can ease the symptoms of heart failure, such as breathlessness and swelling.However, diuretics may have some side effects, such as loss of potassium, which can affect the heart and require regular blood tests and dietary changes.Diuretics can also cause other electrolyte abnormalities, such as hyponatremia, hypomagnesemia, hypocalcemia, and metabolic alkalosis. Electrolyte disturbances can have serious consequences for the heart function and rhythm, as well as other organs.
Choice A is wrong because fluid retention is the opposite of what diuretics do.
Diuretics reduce fluid retention by increasing urine output and decreasing blood volume.
Choice B is wrong because hypotension is not a direct effect of diuretics on the heart, but rather a consequence of reduced blood volume and vasodilation.
Hypotension can occur with diuretic use, especially if the dose is too high or the patient is dehydrated, but it is not a specific condition caused by diuretics.
Choice C is wrong because hyperglycemia is not related to diuretics or heart failure.
Hyperglycemia is a condition of high blood sugar, which can be caused by diabetes or other factors.
Diuretics do not affect blood sugar levels directly, although some diuretics may interact with diabetes medications and affect their efficacy.
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