Which drug class is capable of dissolving blood clots?
Salicylates.
Antiplatelets.
Anticoagulants.
Thrombolytic agents.
The Correct Answer is D
Thrombolytic agents are a classification of drugs that dissolve blood clots by activating the enzyme plasmin, which breaks down the proteins (fibrins) that form clots. They are used for serious conditions, such as stroke, pulmonary embolism, or heart attack when the blood flow needs to be restored quickly.
Choice A is wrong because salicylates are anti-inflammatory drugs that inhibit the synthesis of prostaglandins, which are involved in inflammation and pain. They also have antiplatelet effects, but they do not dissolve existing clots.
Choice B is wrong because antiplatelets are drugs that prevent platelets from sticking together and forming clots. They are used to prevent clotting in conditions such as coronary artery disease, stroke, or peripheral arterial disease. They do not dissolve existing clots either.
Choice C is wrong because anticoagulants are drugs that prevent clots from forming by interfering with the clotting factors that are normally present in the blood.
They are used to treat or prevent conditions such as deep vein thrombosis, pulmonary embolism, or atrial fibrillation. They do not dissolve existing clots.
Normal ranges for clotting factors vary depending on the laboratory and the method used, but some common values are:
• Prothrombin time (PT): 11 to 13 seconds
• International normalized ratio (INR): 0.8 to 1.2
• Activated partial thromboplastin time (aPTT): 25 to 35 seconds
• Fibrinogen: 200 to 400 mg/dL
• D-dimer: less than 0.5 mcg/mL
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
HDL stands for high-density lipoprotein, which is a type of cholesterol that carries excess cholesterol from other parts of the body to the liver, where it can be removed.
HDL is sometimes called “good” cholesterol because it helps protect against heart disease.Having high HDL levels is not a characteristic of metabolic syndrome, but rather a protective factor.
Metabolic syndrome is a group of conditions that increase the risk of heart disease, stroke, and type 2 diabetes.These conditions include:
• Low HDLs (choice A): Having low levels of HDL cholesterol is a risk factor for metabolic syndrome, as it means there is less “good” cholesterol to remove excess cholesterol from the blood vessels.
• Type II diabetes mellitus (choice B): This is a condition where the body does not use insulin properly, leading to high blood sugar levels.
Insulin is a hormone that helps the cells take up glucose from the blood.
Insulin resistance is a key feature of metabolic syndrome.
• Hypertension (choice C): This means having high blood pressure, which can damage the heart and blood vessels over time.
High blood pressure is often associated with obesity and insulin resistance, which are common in metabolic syndrome.
• Abdominal obesity (choice E): This means having excess fat around the waist and trunk, also known as central or visceral obesity.
This type of fat is more harmful than fat in other parts of the body, as it can release inflammatory substances that affect the metabolism and increase the risk of cardiovascular disease.
• Hyperglycemia (choice F): This means having high blood sugar levels, which can damage the blood vessels and organs over time.
Hyperglycemia can result from insulin resistance or type 2 diabetes, which are both components of metabolic syndrome.
The normal ranges for some of these conditions are:
• HDL cholesterol: more than 40 mg/dL for men and more than 50 mg/dL for women
• Blood pressure: less than 120/80 mmHg
• Blood sugar: less than 100 mg/dL after fasting or less than 140 mg/dL two hours after eating
• Waist circumference: less than 40 inches for men and less than 35 inches for women
Correct Answer is A
Explanation
Atorvastatin is a type ofstatin, which are the most potent antilipidemic agents, and have proven to lower the risk of myocardial infarction by reducing the levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the blood.Statins also slightly increase the level of high-density lipoprotein (HDL) cholesterol, which is beneficial for cardiovascular health.
Choice B, niacin, is a type ofnicotinic acid, which can lower LDL cholesterol and triglycerides, and increase HDL cholesterol, but it is less effective than statins and has more side effects, such as flushing, itching, and liver toxicity.
Choice C, gemfibrozil, is a type offibric acid derivative, which can lower triglycerides and increase HDL cholesterol, but have little effect on LDL cholesterol.They are mainly used for patients with high triglyceride levels or low HDL cholesterol levels.
Choice D, amlodipine, is not an antilipidemic agent at all.It is a type ofcalcium channel blocker, which is used to treat hypertension and angina by relaxing the blood vessels and reducing the workload of the heart.
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