Which drug class is capable of dissolving blood clots?
Salicylates.
Antiplatelets.
Anticoagulants.
Thrombolytic agents.
The Correct Answer is D
Thrombolytic agents are a classification of drugs that dissolve blood clots by activating the enzyme plasmin, which breaks down the proteins (fibrins) that form clots. They are used for serious conditions, such as stroke, pulmonary embolism, or heart attack when the blood flow needs to be restored quickly.
Choice A is wrong because salicylates are anti-inflammatory drugs that inhibit the synthesis of prostaglandins, which are involved in inflammation and pain. They also have antiplatelet effects, but they do not dissolve existing clots.
Choice B is wrong because antiplatelets are drugs that prevent platelets from sticking together and forming clots. They are used to prevent clotting in conditions such as coronary artery disease, stroke, or peripheral arterial disease. They do not dissolve existing clots either.
Choice C is wrong because anticoagulants are drugs that prevent clots from forming by interfering with the clotting factors that are normally present in the blood.
They are used to treat or prevent conditions such as deep vein thrombosis, pulmonary embolism, or atrial fibrillation. They do not dissolve existing clots.
Normal ranges for clotting factors vary depending on the laboratory and the method used, but some common values are:
• Prothrombin time (PT): 11 to 13 seconds
• International normalized ratio (INR): 0.8 to 1.2
• Activated partial thromboplastin time (aPTT): 25 to 35 seconds
• Fibrinogen: 200 to 400 mg/dL
• D-dimer: less than 0.5 mcg/mL
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Digibind is the trade name forantidigoxin, which is an antibody made up of anti-digoxin immunoglobulin fragments.It is thespecific antidoteto digoxin toxicity, which can occur even when the serum digoxin concentration is within the therapeutic range.Digoxin toxicity causes anorexia, nausea, vomiting, neurological symptoms and arrhythmias.
Choice A, Protamine sulfate, is wrong because it is the antidote for heparin overdose, not digoxin toxicity.
Protamine sulfate reverses the anticoagulant effect of heparin by binding to it and forming a stable complex.
Choice B, Acetylcysteine, is wrong because it is the antidote for acetaminophen overdose, not digoxin toxicity.
Acetylcysteine replenishes glutathione, which is depleted by acetaminophen metabolites that cause hepatotoxicity.
Choice D, Vitamin K, is wrong because it is the antidote for warfarin overdose, not digoxin toxicity.
Vitamin K restores the synthesis of clotting factors that are inhibited by warfarin.
Normal ranges for serum digoxin concentration are 0.6 to 1.2 nanomol/L (0.5 to 0.9 nanograms/mL) for heart failure and unknown for atrial fibrillation without heart failure.
Normal ranges for serum potassium level are 3.5 to 5.0 mmol/L and for serum magnesium level are 0.7 to 1.0 mmol/L.
Correct Answer is B
Explanation
PT stands for prothrombin time, which is a measure of how long it takes the blood to clot. INR stands for international normalized ratio, which is a standardized way of reporting the PT result. Warfarin is a blood thinner that works by slowing down the clotting process.Therefore, people who take warfarin need to have their PT/INR monitored regularly to make sure they are getting the right dose and not bleeding too much or too little.
Choice A is wrong because PTT stands for partial thromboplastin time, which is another measure of blood clotting that is not affected by warfarin.PTT is used to monitor heparin, another type of blood thinner.
Choice C is wrong because CBC stands for complete blood count, which is a test that measures the number and types of cells in the blood, such as red blood cells, white blood cells and platelets.CBC can show if there is anemia, infection or bleeding, but it does not measure the effect of warfarin on clotting.
Choice D is wrong because LFTs stand for liver function tests, which are a group of tests that check how well the liver is working.
LFTs can show if there is liver damage or disease, which can affect how warfarin is metabolized and cleared from the body.However, LFTs do not directly measure the effect of warfarin on clotting.
The normal range for PT/INR varies depending on the laboratory and the reason for taking warfarin.
Generally, the normal range for PT is 10 to 13 seconds, and the normal range for INR is 1.1 or below for healthy people.For people taking warfarin, the target INR range depends on their condition and risk factors, but it is usually between 2.0 and 3.0.
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