The antidote to warfarin toxicity is what?
Vitamin B12.
Vitamin K.
Calcium gluconate.
Protamine sulfate
The Correct Answer is B
Vitamin K is the antidote for warfarin toxicity because it can reverse the effects of warfarin by restoring the clotting factors. Warfarin is an oral anticoagulant that works by inhibiting vitamin K epoxide reductase, an enzyme that activates vitamin K in the body. Vitamin K is needed for the synthesis of active coagulation factors, such as II, VII, IX and X. By blocking vitamin K, warfarin reduces the blood’s clotting activity and prevents the formation of blood clots.
Choice A is wrong because vitamin B12 is not involved in the coagulation cascade. Vitamin B12 is mainly involved in DNA synthesis, red blood cell production and nerve function.
Choice C is wrong because calcium gluconate is not an antidote for warfarin toxicity. Calcium gluconate is used to treat low blood calcium levels or hypocalcemia. Calcium is also a cofactor for some coagulation factors, but it does not reverse the effects of warfarin.
Choice D is wrong because protamine sulfate is not an antidote for warfarin toxicity.
Protamine sulfate is used to reverse the effects of heparin, another type of anticoagulant that works by inhibiting thrombin and factor Xa.
Protamine sulfate does not affect the vitamin K-dependent coagulation factors that are inhibited by warfarin.
Normal ranges for coagulation tests that are affected by warfarin are:
• Prothrombin time (PT): 11 to 13.5 seconds
• International normalized ratio (INR): 0.8 to 1.2
• Activated partial thromboplastin time (aPTT): 25 to 35 seconds
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
This is because potassium sparing diuretics do not lower potassium levels in the blood, unlike some other types of diuretics. Potassium is an important electrolyte that helps regulate nerve and muscle functions, especially the heart. Low potassium levels can cause irregular heartbeats and other problems.Therefore, people who take diuretics should avoid foods that are high in potassium, such as bananas, oranges, tomatoes, and potatoes, unless they are taking potassium sparing diuretics.
Choice A is wrong because thiazide diuretics, such as hydrochlorothiazide, can cause low potassium levels in the blood and increase the risk of arrhythmias.
People who take thiazide diuretics may need to take potassium supplements or eat more potassium-rich foods.
Choice B is wrong because osmotic diuretics, such as mannitol, do not affect potassium levels in the blood.
They work by increasing the amount of water in the urine, but do not alter the electrolyte balance.
Osmotic diuretics are mainly used to treat brain swelling or glaucoma.
Choice D is wrong because loop diuretics, such as lasix, can also cause low potassium levels in the blood and increase the risk of arrhythmias.
People who take loop diuretics may also need to take potassium supplements or eat more potassium-rich foods.
Normal ranges for potassium in the blood are 3.5 to 5.0 millimoles per liter (mmol/L).
Correct Answer is D
Explanation
Taking a loop diuretic with supper is not advisable because it can cause nocturia, which is the need to urinate frequently at night. This can disrupt sleep and affect quality of life.Loop diuretics should be taken in the morning or early afternoon to avoid this problem.
Choice A is wrong because weighing oneself each day before breakfast is a good way to monitor fluid balance and detect any signs of fluid retention or dehydration.This can help adjust the dose of the loop diuretic as needed.
Choice B is wrong because contacting the healthcare provider if shortness of breath returns is a sensible precaution and indicates awareness of the symptoms of worsening heart failure.Shortness of breath is caused by fluid accumulation in the lungs, which loop diuretics help to prevent or reduce.
Choice C is wrong because having a banana with breakfast every morning is a good source of potassium, which can help prevent hypokalemia, a common side effect of loop diuretics.Loop diuretics increase the excretion of potassium in the urine, which can lead to low blood levels of potassium and cause muscle weakness, cramps, fatigue, arrhythmias, and increased sensitivity to digoxin.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.
