Which drug class should not be used when a patient is taking nitrates?
Erectile dysfunction drugs.
Alpha-adrenergic blockers.
Calcium channel blockers.
Beta-adrenergic blockers.
The Correct Answer is A
Erectile dysfunction drugs should not be used when a patient is taking nitrates. This is because both types of drugs cause blood vessels to dilate, which can lead to a dangerous drop in blood pressure. This can increase the risk of heart attack, stroke or fainting.
Choice B is wrong because alpha-adrenergic blockers are sometimes used together with nitrates to treat high blood pressure and angina. They work by relaxing the smooth muscles of the blood vessels, which lowers blood pressure and improves blood flow.
Choice C is wrong because calcium channel blockers are also used to treat high blood pressure and angina. They work by blocking the entry of calcium into the muscle cells of the heart and blood vessels, which reduces the force of contraction and relaxes the blood vessels.
Choice D is wrong because beta-adrenergic blockers are another class of drugs that can be used with nitrates to treat high blood pressure and angina. They work by blocking the effects of adrenaline on the heart and blood vessels, which slows down the heart rate and lowers blood pressure.
Normal ranges for blood pressure vary depending on age, gender and other factors, but generally they are between 90/60 mmHg and 120/80 mmHg for healthy adults.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Vitamin K is the antidote for warfarin toxicity because it can reverse the effects of warfarin by restoring the clotting factors.Warfarin is an oral anticoagulant that works by inhibiting vitamin K epoxide reductase, an enzyme that activates vitamin K in the body.Vitamin K is needed for the synthesis of active coagulation factors, such as II, VII, IX and X.By blocking vitamin K, warfarin reduces the blood’s clotting activity and prevents the formation of blood clots.
Choice A is wrong because vitamin B12 is not involved in the coagulation cascade.Vitamin B12 is mainly involved in DNA synthesis, red blood cell production and nerve function.
Choice C is wrong because calcium gluconate is not an antidote for warfarin toxicity.Calcium gluconate is used to treat low blood calcium levels or hypocalcemia.Calcium is also a cofactor for some coagulation factors, but it does not reverse the effects of warfarin.
Choice D is wrong because protamine sulfate is not an antidote for warfarin toxicity.
Protamine sulfate is used to reverse the effects of heparin, another type of anticoagulant that works by inhibiting thrombin and factor Xa.
Protamine sulfate does not affect the vitamin K-dependent coagulation factors that are inhibited by warfarin.
Normal ranges for coagulation tests that are affected by warfarin are:
• Prothrombin time (PT): 11 to 13.5 seconds
• International normalized ratio (INR): 0.8 to 1.2
• Activated partial thromboplastin time (aPTT): 25 to 35 seconds
Correct Answer is A
Explanation
Intermittent claudication is a condition where leg pain is produced upon increased activity and ischemia to tissues, but then the pain is reduced with rest.This is because the lack of oxygen to the muscles causes pain, and resting allows the blood flow to resume.
Choice B, sporadic ischemia, is wrong because it is not a specific condition, but a general term for reduced blood supply to a tissue or organ.
Choice C, angina, is wrong because it is a chest pain caused by reduced blood flow to the heart, not the legs.
Choice D, paresthesia, is wrong because it is a sensation of tingling, numbness, or prickling in the skin, not pain.
It can be caused by various conditions, such as nerve damage, diabetes, or Raynaud’s disease.
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