The emergency department nurse provides care for a 50-year-old male patient with septic shock. The nurse recalls that the renin- angiotensin system is activated during which stage of shock?
Initial stage
Progressive stage
Refractory stage
Compensatory stage
The Correct Answer is D
In the compensatory stage of shock, the body initiates various mechanisms to maintain perfusion to vital organs and restore homeostasis. Activation of the renin-angiotensin system is one of the compensatory responses. The decreased blood flow and oxygen delivery to the kidneys stimulate the release of renin from the kidneys. Renin acts on angiotensinogen, converting it into angiotensin I, which is further converted to angiotensin II by the action of angiotensin-converting enzyme (ACE). Angiotensin II is a potent vasoconstrictor and also stimulates the release of aldosterone, leading to sodium and water retention. These mechanisms aim to increase blood pressure and cardiac output and restore fluid balance.
A. The initial stage of shock in (option A) is incorrect because it is characterized by inadequate tissue perfusion and the activation of various compensatory mechanisms, including the release of stress hormones. However, the renin-angiotensin system is not specifically mentioned as activated in this stage.
B. The progressive stage of shock in (option B) is incorrect because it occurs when compensatory mechanisms fail to maintain adequate perfusion, leading to worsening hypoperfusion and organ dysfunction. The renin-angiotensin system continues to be activated during this stage, but it is primarily associated with the compensatory stage.
C. The refractory stage of shock in (option C) is incorrect because it is the stage of severe and prolonged hypoperfusion, where organ failure becomes irreversible. The renin-angiotensin system may still be activated, but it is not the primary focus of this stage.
Therefore, the activation of the renin-angiotensin system occurs during the compensatory stage of shock.
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Related Questions
Correct Answer is C
Explanation
In septic shock, one of the key goals of management is to restore and maintain adequate intravascular volume. However, in this case, the patient's urine output is low (30 mL/hr for the past 3 hours), suggesting inadequate renal perfusion and potential fluid overload.
Administering additional normal saline at an increased rate (250 mL/hr) without addressing the low urine output could potentially exacerbate fluid overload and further compromise the patient's condition.
A. Administer hydrocortisone (Solu-Cortef) 100 mg IV in (option A) is incorrect because: Hydrocortisone is commonly used in septic shock to help stabilize blood pressure and modulate the inflammatory response.
B. Giving PRN furosemide (Lasix) 40 mg IV in (option B) is incorrect because Furosemide, a loop diuretic, can be administered as needed to address fluid overload or to increase urine output if there is evidence of volume overload.
D. Titrate norepinephrine (Levophed) to keep systolic BP >90 mm Hg in (option D) is incorrect because: Norepinephrine is a vasopressor commonly used in septic shock to increase systemic vascular resistance and maintain adequate blood pressure.
Correct Answer is D
Explanation
Beck's triad consists of three classic clinical manifestations that are suggestive of cardiac tamponade, which is the compression of the heart by accumulated fluid or blood within the pericardial sac. The three components of Beck's triad include:
A. Muffled heart tones in (option A) are incorrect because Cardiac tamponade can dampen or muffle heart sounds due to the presence of fluid or blood around the heart, which can impair sound transmission.
B. Marked hypotension in (option B) is incorrect because Cardiac tamponade can cause decreased cardiac output, leading to hypotension, which is characterized by low blood pressure.
C. Distended jugular veins in (option C) is incorrect because Elevated venous pressure resulting from impaired filling and elevated right-sided heart pressures can lead to jugular vein distension, which is commonly seen in cardiac tamponade.
However, widening pulse pressure (the difference between systolic and diastolic blood pressure) is not typically part of Beck's triad. Widening pulse pressure is associated with her conditions such as aortic regurgitation, hyperthyroidism, or conditions involving increased stroke volume, rather than cardiac tamponade specifically.
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