A nurse is to administer Dobutamine (Dobutrex) 2.5 mcg/kg/min IV to a patient with severe heart failure who weighs 130 pounds. The pharmacy prepares a solution of 250 mg of Dobutrex in 500 mL D5W. How many mL of the medication should be administered to the patient per hour? Round your answer to the nearest whole number.

Answer and Explanation

The Correct Answer is ["18"]

Step 1: Convert the patient's weight from pounds to kilograms. 130 pounds ÷ 2.205 (1 pound = 0.453592 kilograms) ≈ 58.97 kilograms

Step 2: Calculate the total dosage of Dobutamine required per hour based on the weight-specific dose. 2.5 mcg/kg/min × 58.97 kg = 147.425 mcg/min

Step 3: Calculate the infusion rate (mL/hr) using the concentration of Dobutamine in the prepared solution. The solution contains 250 mg of Dobutamine in 500 mL, which means there are 250,000 mcg of Dobutamine in 500 mL. To determine the mL/hr, divide the required dosage (147.425 mcg/min) by the amount of Dobutamine in 500 mL (250,000 mcg) and multiply by 500 mL (volume of the solution).

(147.425 mcg/min ÷ 250,000 mcg) × 500 mL ≈ 0.295 mL/min

To get the mL/hr, we convert the rate from minutes to hours (60 minutes = 1 hour):

0.295 mL/min × 60 min/hr ≈ 17.7 mL/hr

Round the answer to the nearest whole number:

Approximately 18 mL/hr of Dobutamine should be administered to the patient.

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Free Nursing Study Resources

Correct Answer is A,B,D,C

Explanation

A. Decreased blood volume: Burn injuries can lead to fluid loss, primarily through damaged skin. This fluid loss causes a decrease in blood volume, leading to hypovolemia. Hypovolemia contributes to decreased cardiac output and tissue perfusion.
B. Increased vascular permeability: Burn injuries cause an inflammatory response, leading to increased vascular permeability. This increased permeability allows fluid, electrolytes, and proteins to leak from the intravascular space into the interstitial space.
C. Development of edema: The increased vascular permeability and fluid leakage lead to the development of edema. Edema occurs as fluid accumulates in the interstitial spaces, further contributing to tissue swelling and compromised perfusion.
D. Increased peripheral resistance: In response to decreased blood volume and tissue hypoperfusion, the body activates compensatory mechanisms to maintain blood pressure and tissue perfusion. One of these mechanisms is increased peripheral resistance, which occurs as blood vessels constrict to maintain blood pressure. Increased peripheral resistance helps redirect blood flow to vital organs but also contributes to increased workload on the heart.
Therefore, the correct sequential order of events involved in burn shock following a patient's exposure to burns is:
A. Decreased blood volume B. Increased vascular permeability D. Development of edema C. Increased peripheral resistance

A. 18 Ml B. 5480 Ml C. 6,480 mL D. 4234 mL

Correct Answer is C

Explanation

Heart rate: 72 beats per minute Stroke volume: 90 mL/contraction

Cardiac output = Heart rate × Stroke volume

Cardiac output = 72 beats/minute × 90 mL/contraction

To simplify the calculation, you can convert the units:

72 beats/minute × 90 mL/contraction = (72 × 90) beats/minute × mL/contraction

Now, perform the multiplication:

72 × 90 = 6,480

Therefore, the cardiac output is 6,480 mL per minute.

The correct answer is:

C. 6,480 mL

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Naxlex Comprehensive Predictor Exams

A 32-year-old male patient sustains 78% TBSA burn and is currently admitted to the burn unit. Which sequential order would the nurse arrange the events involved in burn shock following a patient's exposure to burns?

Correct Answer is A,B,D,C

Explanation

What is the cardiac output of a patient whose heart rate is 72 beats per minute with a stroke volume of 90 mL/contraction?

Correct Answer is C

Explanation

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