The emergency department nurse is preparing an infusion of IV alteplase for a client who suffered a cerebrovascular accident (CVA). Which of the following statements is accurate about the administration of alteplase?
The drug is not given to clients who are taking anticoagulant or antiplatelet therapy.
The drug is given in a bolus over the first 3 minutes followed by a continuous infusion.
The recommended time for drug administration is within 90 minutes after admission to the emergency department.
The maximum dosage of the drug, including the bolus, is 120 mg intravenously.
The Correct Answer is B
A. While there are strict inclusion and exclusion criteria for alteplase administration, this statement is overly broad. There are certain situations where anticoagulant or antiplatelet therapy can be managed to allow for alteplase use.
B. Alteplase is administered as a bolus over 1 minute, followed by an infusion over 60 minutes.
C. While time is critical in stroke treatment, the recommended window for alteplase administration is typically within 3-4.5 hours of symptom onset.
D. The maximum dose of alteplase is actually 0.9 mg/kg, up to a maximum of 90 mg.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. There can be slight variations in pupil size but the difference described (one pupil enlarged and fixed, the other constricted and reactive to light) is not considered normal.
B. Age-related changes in pupil size typically involve a gradual decrease in pupil size, not a sudden and dramatic difference between the two eyes.
C. Unequal pupil size, especially when one pupil is fixed and dilated, is a classic sign of increased intracranial pressure (ICP), often caused by head trauma.
D. Exposure to light would cause both pupils to constrict, not one to dilate and fix.
Correct Answer is ["0.5"]
Explanation
- Convert the prescribed dose of digoxin from micrograms to milligrams
1 mg equals 1000 mcg.
Therefore, 125 mcg is equivalent to 0.125 mg.
Since the available tablets are 0.25 mg each, you would divide the required dose (0.125 mg) by the strength of the available tablet (0.25 mg).
This calculation results in 0.5
The nurse should administer half a tablet per dose.
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