The basic event in the formation of a blood clot is the change of:
Thrombin to prothrombin.
Fibrinogen to fibrin.
Vitamin K to prothrombin.
Fibrin to fibrinogen.
The Correct Answer is B
This is because fibrinogen is a soluble protein in the blood plasma that is converted to insoluble fibrin strands by the enzyme thrombin during blood clotting. Fibrin forms a mesh-like network that traps platelets and other blood cells to form a clot.
Choice A is wrong because thrombin is not converted to prothrombin, but rather prothrombin is converted to thrombin by another enzyme called prothrombinase.
Choice C is wrong because vitamin K is not converted to prothrombin, but rather vitamin K is required for the synthesis of prothrombin and other clotting factors in the liver.
Choice D is wrong because fibrin is not converted to fibrinogen, but rather fibrinogen is converted to fibrin as explained above.
Normal ranges of fibrinogen in the blood are 200 to 400 mg/dL.
Normal ranges of prothrombin time (a measure of how long it takes blood to clot) are 11 to
13.5 seconds.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
As a result of the allergen-antibody reaction, mast cells release histamine.
This is because when mast cells are exposed to an allergen that binds to IgE antibodies attached to their FcɛRI receptors, they release histamine and other inflammatory mediators.
Histamine causes vasodilation, increased capillary permeability, mucus secretion, and smooth muscle contraction, which result in allergic symptoms such as itching, swelling, sneezing, and wheezing.
Mast cells do release histamine in response to allergen-antibody reactions. Some additional sentences are:
Normal ranges of histamine levels vary depending on the tissue and the method of measurement, but they are usually low in healthy individuals and elevated in allergic conditions.
Histamine can be degraded by enzymes such as diamine oxidase and histamine N- methyltransferase, or inhibited by drugs such as antihistamines.
Correct Answer is C
Explanation
Basophils usually account for the smallest percentage of leukocytes in a blood sample. Basophils are a type of white blood cell that is involved in allergic reactions and inflammation.
Choice A is wrong because eosinophils are not the least common type of leukocyte.
Eosinophils are another type of white blood cell that is involved in allergic responses and parasitic infections.
They typically make up about 1-6% of the total leukocyte count.
Choice B is wrong because monocytes are not the least common type of leukocyte.
Monocytes are a type of white blood cell that can differentiate into macrophages and dendritic cells, which are important for phagocytosis and antigen presentation.
They typically make up about 2-10% of the total leukocyte count.
Choice D is wrong because neutrophils are not the least common type of leukocyte.
Neutrophils are a type of white blood cell that are the first responders to bacterial infections and tissue damage.
They typically make up about 55-70% of the total leukocyte count.
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