The basic event in the formation of a blood clot is the change of:
Thrombin to prothrombin.
Fibrinogen to fibrin.
Vitamin K to prothrombin.
Fibrin to fibrinogen.
The Correct Answer is B
This is because fibrinogen is a soluble protein in the blood plasma that is converted to insoluble fibrin strands by the enzyme thrombin during blood clotting. Fibrin forms a mesh-like network that traps platelets and other blood cells to form a clot.
Choice A is wrong because thrombin is not converted to prothrombin, but rather prothrombin is converted to thrombin by another enzyme called prothrombinase.
Choice C is wrong because vitamin K is not converted to prothrombin, but rather vitamin K is required for the synthesis of prothrombin and other clotting factors in the liver.
Choice D is wrong because fibrin is not converted to fibrinogen, but rather fibrinogen is converted to fibrin as explained above.
Normal ranges of fibrinogen in the blood are 200 to 400 mg/dL.
Normal ranges of prothrombin time (a measure of how long it takes blood to clot) are 11 to
13.5 seconds.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Macrophages are the main cells that clear out the cell debris by phagocytosis, a process that involves recognition, engulfment, and degradation of the disposable particles.
Macrophages are professional phagocytes that can be found in various tissues and organs, where they perform efferocytosis, the removal of dead and dying cells.
Choice A is wrong because lymphocytes are not phagocytes, but rather immune cells that mediate adaptive immunity by producing antibodies or killing infected cells.
Choice B is wrong because cytokines are not cells, but rather soluble molecules that regulate inflammation and immunity by acting as signals between cells.
Choice C is wrong because mast cells are not primarily involved in clearing cell debris, but rather in allergic reactions and innate immunity by releasing histamine and other mediators.
Correct Answer is A
Explanation
It is a major component of the lymphatic system and contains T and B lymphocytes.
Choice B is wrong because the spleen does not produce T lymphocytes, but rather stores them.
T lymphocytes are produced in the thymus.
Choice C is wrong because the spleen does not filter lymph, but rather blood. It traps bloodborne microbes and produces an immune response to them.
Choice D is wrong because the spleen consists of one lobe and is located in the upper left abdomen below the diaphragm.
The description in choice D matches the thymus, not the spleen.
The normal size of the spleen in adults is about 12 cm long, 8 cm broad, and 3-4 cm thick, weighing about 200 g.
The normal range of splenic index (the product of length, width, and thickness) is 120-480 cm.
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