An older adult client has been prescribed metformin for the treatment of type 2 diabetes for several years. Which change in the client's laboratory values may demonstrate a need to discontinue the medication?

An increase in serum lactate

A decrease in hemoglobin and hematocrit

An increase in white blood cells

A decrease in potassium accompanied by an increase in sodium

Answer and Explanation

The Correct Answer is A

A. An increase in serum lactate – This is a critical laboratory value that can indicate lactic acidosis, a serious side effect associated with metformin, especially in older adults or those with renal impairment. An increase in serum lactate necessitates discontinuation of the medication.

B. A decrease in hemoglobin and hematocrit – While this change may indicate anemia, it is not directly associated with the need to discontinue metformin. Further evaluation of the cause of anemia would be necessary.

C. An increase in white blood cells – This could indicate an infection or inflammatory process but does not specifically necessitate the discontinuation of metformin.

D. A decrease in potassium accompanied by an increase in sodium – While electrolyte imbalances should be monitored, this change does not directly indicate that metformin should be discontinued.

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Correct Answer is A

Explanation

Schizophrenia is believed to be related to an overactivity of the dopamine system in certain areas of the brain. Antipsychotic medications, which are the primary treatment for schizophrenia, work by blocking dopamine receptors, thereby decreasing the activity of the dopamine system. This is referred to as the dopamine hypothesis of schizophrenia.

A. It should be taken at least 30 minutes before or 2 hours after meals. B. It is best to take it with an antacid C. It should be taken before 09:00 each morning D. The best administration time is at bedtime.

Correct Answer is C

Explanation

Hydrocortisone is a glucocorticoid hormone that is usually prescribed for the treatment of Addison's disease, which is characterized by insufficient production of adrenal hormones. It is important to take hydrocortisone in the morning before 09:00 because this is when the body's natural cortisol levels are at their highest. Taking hydrocortisone at this time can help to mimic the body's natural cortisol production and prevent adrenal crisis. It should be taken with meals to reduce the risk of stomach upset.

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An older adult client has been prescribed metformin for the treatment of type 2 diabetes for several years. Which change in the client's laboratory values may demonstrate a need to discontinue the medication?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is caring for a client who has been diagnosed with schizophrenia. The nurse understands that the client's condition is thought to be most likely related to an increased level of activity of what neurotransmitter?

Correct Answer is A

Explanation

Hydrocortisone has been prescribed to a client for the treatment of Addison's disease What action should the nurse encourage the client to take regarding the selfadministration of this medication?

Correct Answer is C

Explanation

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