The nurse is educating an adult client who has been diagnosed with adrenocortical carcinoma about the prescribed mitotane 6 g P0 in divided doses. Which statement made by the client establishes the need for further clarification? a. "If I have a trauma or go into shock, the drug is temporarily stopped."

Metformin is an oral medication used to lower blood sugar levels in clients with type 2 diabetes. It works by decreasing the production and absorption of glucose in the liver and intestines, respectively. However, metformin is contraindicated in clients with severe infections, as the drug can increase the risk of developing lactic acidosis, a rare but serious complication characterized by the buildup of lactic acid in the bloodstream.

During a severe infection, the body may experience a state of inflammation and stress, which can cause metabolic changes that increase the risk of developing lactic acidosis. Therefore, metformin should be temporarily discontinued in clients with severe infections and resumed only after the infection has been successfully treated and resolved.

In the meantime, the client's diabetic regimen may need to be adjusted to maintain appropriate blood sugar levels. This may include the use of alternative medications such as insulin, which can be used to control blood sugar levels during times of illness or infection. The healthcare provider will determine the appropriate management plan based on the individual client's needs and medical history.

Flumazenil is a medication that is used as an antidote for benzodiazepine overdose, including diazepam. Benzodiazepines are a class of drugs that are used to treat anxiety, insomnia, seizures, and other conditions. However, they can also be abused or taken in excessive doses, leading to overdose.

Flumazenil works by binding to the same receptors in the brain that benzodiazepines bind to, but it has the opposite effect. Flumazenil blocks the activity of benzodiazepines and can rapidly reverse the effects of an overdose, including respiratory depression, sedation, and coma.

It is important to note that flumazenil should only be used in cases of benzodiazepine overdose and should be administered under close medical supervision. Flumazenil may cause seizures in clients who are physically dependent on benzodiazepines, and it should not be used as a substitute for appropriate medical care and monitoring.