A nurse is reviewing the medical record of a client who has schizophrenia and is taking clozapine.
Which of the following findings should the nurse identify as a contraindication to the administration of clozapine?
Heart rate 58/min.
Fasting blood glucose 100 mg/dL.
WBC count 2,900/mm3.
Hgb 14 g/dL.
The Correct Answer is C
Choice A rationale:
Heart rate 58/min. Clozapine, an atypical antipsychotic medication, can cause bradycardia (slow heart rate) as a side effect. However, the heart rate of 58/min is within the normal range for adults, so it is not a contraindication for clozapine administration.
Choice B rationale:
Fasting blood glucose 100 mg/dL. A fasting blood glucose level of 100 mg/dL is within the normal range (70-99 mg/dL) for adults. It is not a contraindication for clozapine administration.
Choice C rationale:
WBC count 2,900/mm3. Clozapine can cause agranulocytosis, a severe reduction in white blood cell (WBC) count, which can lead to increased susceptibility to infections. A WBC count of 2,900/mm3 is significantly below the normal range (4,000-11,000/mm3) and is a contraindication for clozapine administration due to the risk of severe immunosuppression.
Choice D rationale:
Hgb 14 g/dL. Hemoglobin (Hgb) level of 14 g/dL is within the normal range for adult males (13.8-17.2 g/dL) and females (12.1-15.1 g/dL). It is not a contraindication for clozapine administration.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale:
The prescription for Levothyroxine 75 mcg PO daily at 0600 does not require clarification. It provides clear instructions for the medication, including the drug name, dosage, route, and timing. The administration time (0600) is specific, allowing the nurse to administer the medication accurately.
Choice B rationale:
The prescription for Digoxin 250 PO daily contains an error. The dosage (250) is missing the unit of measurement (e.g., mcg or mg). Without the unit, it is impossible to accurately administer the medication. This prescription needs clarification from the prescriber to ensure safe and precise administration.
Choice C rationale:
The prescription for Acetaminophen 650 mg PO Q6 hours does not require clarification. It provides clear instructions for the medication, including the drug name, dosage (650 mg), route (PO), and frequency (every 6 hours). The dosing interval is appropriate and within the normal range for acetaminophen administration.
Choice D rationale:
The prescription for Ceftriaxone 1 g IV Q 24 hours does not require clarification. It provides clear instructions for the medication, including the drug name, dosage (1 g), route (IV), and frequency (every 24 hours). The dosing interval is appropriate for this antibiotic and allows for effective treatment of infections.
Correct Answer is C
Explanation
The correct answer is C. Increased urinary output indicates that furosemide, a loop diuretic, is effective in reducing fluid retention and edema in clients with heart failure. The other findings are not indicative of furosemide effectiveness and may suggest adverse effects or complications. Decreased BUN level may indicate overhydration or liver dysfunction. Decreased hemoglobin level may indicate anemia or bleeding. Increased weight of 0.91 kg (2 lb) may indicate fluid overload or worsening heart failure.
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