A nurse is providing education to a pregnant client about the hormonal changes during pregnancy.

Which hormone is responsible for maintaining the corpus luteum and stimulating fetal growth ?

Increased glomerular filtration rate.

This is because during pregnancy, the renal blood flow and glomerular filtration rate increase to meet the increased metabolic demands of the mother and fetus.

This can result in increased urinary protein excretion, which is usually mild and does not indicate renal damage.

Choice A is wrong because decreased glomerular permeability would reduce the amount of protein that can pass through the glomerulus and into the urine.

Choice B is wrong because decreased protein intake would not affect the urinary protein levels, unless the intake is severely deficient.

Choice D is wrong because increased tubular reabsorption would decrease the amount of protein that is excreted in the urine, as the tubules would reabsorb more protein from the filtrate and return it to the blood.

Serum creatinine and urea are waste products of protein metabolism that are normally filtered by the kidneys and excreted in urine.

In pregnancy, the glomerular filtration rate (GFR) increases by about 50%, which means more creatinine and urea are cleared from the blood.Therefore, serum creatinine and urea levels decrease in pregnancy compared to nonpregnant women.

A. Increased serum creatinine and urea levels are wrong because they indicate impaired kidney function or dehydration, which are not normal in pregnancy.

C. Unchanged serum creatinine and urea levels are wrong because they do not reflect the increased GFR in pregnancy.

D. Increased glomerular filtration rate is correct but it is not a finding regarding serum creatinine and urea levels, which are the focus of the question.

Normal ranges for serum creatinine and urea vary depending on the laboratory and the units used, but based on a nonpregnant reference interval of 45-90 μmol/l (0.51-1.02 mg/dl) for creatinine and 2.5-6.4 mmol/l (7-18 mg/dl) for urea, a serum creatinine of >77 μmol/l (0.87 mg/dl) and a blood urea of >8.5 mmol/l (24 mg/dl) should be considered outside the normal range for pregnancy.