A nurse is preparing to administer digoxin 0.25 mg PO to a client. The amount available is digoxin 0.125 mg tablets. How many tablets should the nurse administer to the client?

(Round to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

A. Food, Drug and Cosmetic Act (FD&C Act): This act sets the groundwork for food and drug regulations, but it's not the specific legislation governing dietary supplements. While FD&C Act applies to some aspects of supplements, DSHEA has more specific regulations.

B. Joint Commission on the Accreditation of Healthcare Organizations (JCAHO): This organization focuses on accrediting healthcare facilities, not regulating supplements.

C. Health and Human Services (HHS): HHS is a broad department encompassing various healthcare agencies, but DSHEA is the specific act within HHS that governs supplements.

D. Dietary Supplement Health and Education Act (DSHEA): This 1994 act specifically addresses dietary supplements, outlining regulations for labeling, manufacturing, and marketing. It places the responsibility for ensuring the safety and effectiveness of supplements on the manufacturers, unlike prescription drugs approved by the FDA.

A. Vitamin K: Vitamin K is the antidote for warfarin, not heparin. Warfarin works by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver. Therefore, vitamin K is used to reverse the effects of warfarin in cases of over-anticoagulation. It does not reverse the effects of heparin.

B. Deferoxamine: Deferoxamine is a chelating agent used to treat iron toxicity and aluminum overload. It is not indicated for reversing the effects of heparin.

C. Acetylcysteine: Acetylcysteine is used as an antidote for acetaminophen (paracetamol) overdose. It is not indicated for reversing the effects of heparin.

D. Protamine sulfate: This is the correct answer. Protamine sulfate is the antidote for heparin. It works by binding to heparin to form a stable complex, thereby neutralizing its anticoagulant effects. Protamine sulfate is commonly used in clinical practice to reverse the effects of heparin in situations such as hemorrhage or when rapid reversal of anticoagulation is needed, such as before surgery.