The most common adverse effect of epoetin alfa is:

Nausea and vomiting

Orthostatic hypotension

Hypertension

Dizziness

Answer and Explanation

The Correct Answer is C

A. Nausea and vomiting: Nausea and vomiting can occur with epoetin alfa, but it's not the most common side effect.

B. Orthostatic hypotension: This is not a common side effect of epoetin alfa. Orthostatic hypotension is a decrease in blood pressure upon standing.

C. Hypertension: Epoetin alfa stimulates the production of red blood cells. When the red blood cell count increases too quickly, it can lead to increased blood pressure, which is the most common adverse effect.

D. Dizziness: Dizziness can occur with epoetin alfa, but it's less common than hypertension.

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Correct Answer is C

Explanation

White Blood Cell Count (WBC): WBCs are part of the immune system and play a role in fighting infections. However, they are not directly involved in hemostasis or clot formation. WBCs do not adhere to the vessel wall during hemostasis.
Activated Partial Thromboplastin Time (aPTT): aPTT measures the time it takes for blood to clot. It is primarily used to monitor heparin therapy, not warfarin. aPTT is not specific for warfarin monitoring.
Prothrombin Time (PT): PT measures how quickly blood clots. It is used to monitor warfarin therapy and assess clotting factors. PT is essential for monitoring warfarin effectiveness.
Platelet Count: Platelets are crucial for clot formation. Platelet count helps assess platelet function. Platelets play a direct role in hemostasis.

A. LMWHs produce a more stable effect on coagulation; thus, fewer lab tests are needed. B. LMWHs may be given by the oral route C. LMWHs have a short duration of action D. LMWHs possess greater anticoagulant activity

Correct Answer is A

Explanation

A. LMWHs produce a more stable effect on coagulation; thus, fewer lab tests are needed: Correct LMWHs have a more predictable anticoagulant response compared to unfractionated heparin, resulting in a more stable effect on coagulation. Because of their predictable response, routine monitoring of coagulation parameters, such as activated partial thromboplastin time (aPTT), is typically not required with LMWH therapy, unlike with unfractionated heparin.

B. LMWHs may be given by the oral route: Incorrect. LMWHs are administered by the subcutaneous route.

C. LMWHs have a short duration of action: Incorrect. LMWHs have a longer duration of action compared to unfractionated heparin.

D. LMWHs possess greater anticoagulant activity: incorrect. LMWHs generally have less potent anticoagulant activity compared to unfractionated heparin, but their more predictable response and longer half-life make them advantageous in many clinical scenario

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The most common adverse effect of epoetin alfa is:

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Naxlex Comprehensive Predictor Exams

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Correct Answer is C

Explanation

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Correct Answer is A

Explanation

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