The healthcare provider prescribes clopidogrel (Plavix) for a patient at risk for a myocardial infarction. While instructing the patient about the adverse effects and precautions associated with this drug, the nurse tells him that the following drugs should not be used while on clopidogrel unless the doctor is consulted. (Select all that apply.)
alteplase (Activase)
Diltiazem
Ibuprofen
Aspirin
Coumadin
Correct Answer : A,B,C,D,E
A. Alteplase (Activase): Alteplase is a thrombolytic agent used to dissolve blood clots. Concurrent use with clopidogrel, an antiplatelet medication, can increase the risk of bleeding due to additive effects on clotting. Therefore, it's important to consult the doctor before using these medications together.
B. Diltiazem: Diltiazem is a calcium channel blocker used to treat hypertension and certain heart rhythm disorders. Diltiazem will decrease the level or effect of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Therefore, it's advisable to consult the doctor before using these medications together.
C. Ibuprofen: Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. Like other NSAIDs, it can increase the risk of bleeding when taken with clopidogrel. Therefore, it's important to consult the doctor before using these medications together.
D. Aspirin: Aspirin is another antiplatelet medication commonly used to prevent heart attacks and strokes. Combining clopidogrel with aspirin can increase the risk of bleeding without significantly improving outcomes in most cases. However, in some situations, such as after certain cardiac procedures, dual antiplatelet therapy (clopidogrel plus aspirin) may be prescribed under close medical supervision. Therefore, it's crucial to consult the doctor before using these medications together.
E. Coumadin (warfarin): Coumadin is an anticoagulant medication used to prevent blood clots. Concurrent use with clopidogrel can increase the risk of bleeding. Therefore, it's essential to consult the doctor before using these medications together.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["23"]
Explanation
To determine how many milliliters (mL) of potassium chloride the nurse should administer to provide 30 mEq, we can set up a proportion:
20 mEq is contained in 15 mL. So, to find out how many mL contain 30 mEq, we can set up the proportion:
20 mEq:15 mL=30 mEq:𝑥 mL20mEq:15mL=30mEq:xmL
Cross multiply:
20×𝑥=15×3020×x=15×30
20𝑥=45020x=450
Now, solve for 𝑥x:
𝑥=45020x=20450
𝑥=22.5x=22.5
So, the nurse should administer approximately 22.5 mL of potassium chloride.
Rounded to the nearest whole number, this would be 23 mL.
Therefore, the nurse should administer 23 mL of potassium chloride.
Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"A"}
Explanation
a. Hemostasis: Hemostasis refers to the process of stopping bleeding or preventing excessive blood loss. It involves several steps, including vasoconstriction, platelet aggregation, and clot formation. Hemostasis is the correct answer because it directly addresses the stopping of blood flow to protect the body from injury.
b. Thrombolytics: Thrombolytics are medications used to dissolve blood clots. They are not the natural mechanism for stopping blood flow. Thrombolytics are not the correct answer in this context.
c. Hematopoiesis: Hematopoiesis is the process of forming blood cells (including red blood cells, white blood cells, and platelets) in the bone marrow. It is essential for maintaining blood cell populations but does not directly stop blood flow. Hematopoiesis is not related to stopping blood flow.
d. Anticoagulation: Anticoagulation refers to preventing blood clot formation. While it is important for certain medical conditions, it does not directly stop blood flow. Anticoagulation is not the primary mechanism for stopping bleeding.
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