A nurse is preparing a client for discharge home after an admission for bilateral pulmonary emboli. The client is prescribed warfarin in addition to regular daily medications. Which of the following actions should the nurse take?
Advise the client that over-the-counter medications remain safe to consume as needed.
Consult the pharmacist about potential interactions between the client’s regular medications and warfarin.
Recommend the client take warfarin at the same time as other medications.
Tell the client they can continue to drink cranberry juice while taking warfarin.
The Correct Answer is B
Choice A reason: Advising over-the-counter medications as safe is incorrect, as many, like NSAIDs, increase warfarin’s bleeding risk by inhibiting platelets or affecting liver metabolism. Warfarin’s narrow therapeutic index requires careful management to prevent hemorrhage, making broad safety claims dangerous without specific evaluation.
Choice B reason: Consulting the pharmacist identifies interactions with warfarin, a vitamin K antagonist metabolized by CYP450 enzymes. Many drugs alter warfarin’s efficacy, risking thrombosis or bleeding. Pharmacist expertise ensures safe polypharmacy, maintaining therapeutic INR levels critical for managing pulmonary emboli effectively.
Choice C reason: Recommending warfarin with other medications ignores interaction risks and timing needs. Warfarin’s absorption is unaffected by timing, but CYP450 interactions can alter INR. This advice is irrelevant to safety, missing the need for individualized regimen assessment to prevent complications in anticoagulation therapy.
Choice D reason: Cranberry juice may enhance warfarin’s effect by inhibiting CYP2C9, increasing INR and bleeding risk. Advising its use without monitoring is unsafe, as dietary factors can destabilize anticoagulation, potentially causing hemorrhage in clients with pulmonary emboli, requiring careful dietary guidance.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: Varicella, a viral infection, is not treated with antibiotics, which target bacteria. Returning to school after 24 hours of antibiotics is incorrect, as contagiousness persists until lesions crust, typically 5-7 days, risking transmission if the child returns prematurely.
Choice B reason: A negative titer result indicates immunity or resolved infection but is not a practical criterion for school return. Varicella contagiousness depends on lesion crusting, not serology, which is complex and unnecessary when clinical signs confirm reduced infectivity in affected children.
Choice C reason: Fever subsidence does not ensure non-contagiousness in Varicella. The virus spreads via respiratory droplets and lesions until crusted. Allowing return based on fever ignores transmission risk, as active lesions remain infectious, potentially spreading the virus in school settings.
Choice D reason: Varicella is contagious until lesions crust over, typically 5-7 days post-rash. Crusting indicates the end of viral shedding, ensuring safety for school return. This aligns with infection control guidelines, preventing transmission via contact or respiratory routes in communal settings.
Correct Answer is C
Explanation
Choice A reason: Disulfiram is an oral medication, not injectable, used to deter alcohol consumption by causing adverse reactions. Monthly injections apply to drugs like naltrexone, not disulfiram, which requires daily oral dosing to maintain its deterrent effect in alcohol use disorder treatment.
Choice B reason: Taking disulfiram before quitting alcohol is incorrect, as it is started post-abstinence to prevent relapse. Disulfiram inhibits aldehyde dehydrogenase, causing acetaldehyde buildup if alcohol is consumed, making it effective only in alcohol-free clients to deter drinking.
Choice C reason: Avoiding over-the-counter medications with alcohol is correct, as disulfiram causes severe reactions (nausea, flushing) with alcohol ingestion, including from medications like cough syrups. This reflects understanding of disulfiram’s mechanism, ensuring safety by preventing unintended alcohol exposure.
Choice D reason: Continuing disulfiram for 5 years is not standard, as duration varies per treatment plan. Disulfiram supports early abstinence, not fixed long-term use. This statement misrepresents its role, as therapy length depends on individual recovery needs, not a predetermined timeframe.
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