A nurse is caring for a 54-year-old male client who has been admitted to the hospital for peptic ulcer disease. The client will begin a long-term regimen of omeprazole (Prilosec). The nurse understands that the patient will be at high risk for developing which of the following complications? (Select All That Apply.)
Osteoporosis and fractures
Torsades de Pointes
Nausea
Rebound acid hypersecretion
Correct Answer : A,D
A. Long-term use of omeprazole is associated with an increased risk of osteoporosis and fractures due to decreased calcium absorption caused by reduced stomach acid. This complication is significant in older adults, particularly with prolonged therapy.
B. Torsades de Pointes is not a common complication of omeprazole. QT prolongation is more often linked to medications like ondansetron or antiarrhythmics.
C. Nausea is not a typical complication of omeprazole; rather, it is a symptom the drug may help alleviate as part of managing gastrointestinal conditions.
D. Rebound acid hypersecretion can occur after discontinuation of omeprazole. The body may produce an excessive amount of acid to compensate for the previous suppression, leading to worsening symptoms if the medication is abruptly stopped.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Sucralfate does not neutralize gastric acid; antacids are responsible for neutralization.
B. Sucralfate does not mimic endogenous prostaglandins. Medications like misoprostol act as prostaglandins to protect the stomach lining.
C. Sucralfate does not block H2 receptors. Medications like cimetidine or ranitidine work through this mechanism to reduce acid production.
D. Sucralfate creates a viscous, protective barrier that adheres to the ulcer site, shielding it from further damage by gastric acid, bile, and pepsin for up to 6 hours, thereby promoting healing.
Correct Answer is ["A","B","C","D"]
Explanation
A. "Complications of this medication include tardive dyskinesia and prolonged QT interval." This is correct. Metoclopramide (Reglan) can cause side effects such as tardive dyskinesia, a movement disorder, and may prolong the QT interval, which can increase the risk of arrhythmias.
B. "The IV form of this medication is used for control of postoperative and chemotherapy-induced nausea and vomiting, as well as facilitation of small bowel intubation and examination of the GI tract." This is correct. The IV form of metoclopramide is commonly used for these indications, particularly for nausea and vomiting related to chemotherapy or surgery, as well as aiding in small bowel intubation.
C. "Complications of this medication include tardive dyskinesia and sedation." This is correct. In addition to tardive dyskinesia, metoclopramide can also cause sedation, making patients feel drowsy or lethargic.
D. "The oral form is used for diabetic gastroparesis (delayed stomach emptying with gas and bloating) and management of GERD through its ability to increase gastric motility." This is correct. The oral form of metoclopramide is frequently used to treat diabetic gastroparesis by improving gastric emptying, as well as managing gastroesophageal reflux disease (GERD) by enhancing motility.
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