A nurse is teaching a client with a new prescription for metformin (Glucophage). Which of the following findings should the nurse instruct the client to report as an adverse effect of metformin? (Select All That Apply.)
Hypoglycemia
Somnolence
Fluid retention
Hyperglycemia
The Correct Answer is B
A. Metformin does not typically cause hypoglycemia because it works by decreasing hepatic glucose production and improving insulin sensitivity, not directly lowering blood sugar levels.
B. Somnolence could indicate lactic acidosis, a rare but serious adverse effect of metformin that warrants immediate medical attention.
C. Fluid retention is not a known adverse effect of metformin. Other medications, such as certain thiazolidinediones, are associated with this complication.
D. Hyperglycemia is not a typical adverse effect of metformin; instead, it helps manage blood glucose levels in clients with type 2 diabetes mellitus.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Hyperglycemia: While metformin is used to manage blood glucose levels in clients with diabetes, its interaction with contrast dye does not directly lead to hyperglycemia. However, the risk for kidney injury, which can affect glucose regulation, is a concern.
B. Acute renal failure: This is correct. The combination of metformin and iodine-containing contrast dye increases the risk of acute renal failure, also known as contrast-induced nephropathy (CIN). This occurs because contrast agents can cause kidney damage, and metformin is excreted by the kidneys. If renal function is impaired, the buildup of metformin can lead to lactic acidosis.
C. Acute pancreatitis: While acute pancreatitis is a possible side effect of metformin in some individuals, the primary concern with iodine-containing contrast dye is renal failure, not pancreatitis.
D. Acute liver failure: Metformin is primarily metabolized by the kidneys, not the liver, and does not commonly cause liver failure. Renal failure is the more pressing concern with the use of contrast dye in clients taking metformin.
Correct Answer is D
Explanation
A. "This medication may cause increased libido." This is incorrect. Cimetidine (Tagamet) can cause side effects such as decreased libido, especially in men. This occurs because the drug inhibits the action of certain hormones, leading to sexual dysfunction.
B. "You may take this medication with antacids to prevent stomach upset." This is incorrect. Cimetidine should not be taken with antacids because antacids can reduce its absorption and effectiveness. It is advised to space the administration of cimetidine and antacids by at least 1 hour.
C. "This medication will neutralize your stomach acid." This is incorrect. Cimetidine works by blocking histamine receptors (H2 receptors), which reduces the production of stomach acid but does not neutralize it.
D. "This medication may cause decreased libido." This is correct. One of the side effects of cimetidine is reduced libido, particularly in male clients, due to its anti-androgenic effects.
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