A client who regularly takes metformin has developed a severe infection. How will the infection change the established diabetic regimen?

Lisdexamfetamine is a prodrug of dextroamphetamine, which means that it is converted into dextroamphetamine in the body. It is a central nervous system (CNS) stimulant medication used to treat attention deficit hyperactivity disorder (ADHD). Lisdexamfetamine has a lower risk of abuse and dependence compared to other amphetamines, such as methamphetamine, dextroamphetamine, and dextroamphetamine and amphetamine combination products.

Lisdexamfetamine is a long-acting medication that is taken once daily, and it has a slower onset of action compared to other amphetamines. This slower onset of action may make it less attractive for abuse or misuse, as individuals seeking immediate effects may be less likely to use lisdexamfetamine.

However, it is important to note that all amphetamines have the potential for abuse and dependence, and they should only be used under the close supervision of a healthcare provider. Individuals taking amphetamines for ADHD should be closely monitored for signs of misuse, and the medication should be discontinued if misuse or abuse is suspected.

Metformin is an oral medication used to lower blood sugar levels in clients with type 2 diabetes. It works by decreasing the production and absorption of glucose in the liver and intestines, respectively. However, metformin is contraindicated in clients with severe infections, as the drug can increase the risk of developing lactic acidosis, a rare but serious complication characterized by the buildup of lactic acid in the bloodstream.

During a severe infection, the body may experience a state of inflammation and stress, which can cause metabolic changes that increase the risk of developing lactic acidosis. Therefore, metformin should be temporarily discontinued in clients with severe infections and resumed only after the infection has been successfully treated and resolved.

In the meantime, the client's diabetic regimen may need to be adjusted to maintain appropriate blood sugar levels. This may include the use of alternative medications such as insulin, which can be used to control blood sugar levels during times of illness or infection. The healthcare provider will determine the appropriate management plan based on the individual client's needs and medical history.