A client taking atorvastatin becomes an increased serum creatine phosphokinase (CK) level.

The nurse should assess the client for the onset of which problem?

Nausea and vomiting.

Excessive bruising.

Peripheral edema.

Muscle tenderness.

Answer and Explanation

The Correct Answer is D

Atorvastatin is a medication used to lower cholesterol levels in the blood. One of its side eﬀects is muscle damage, which can result in an increase in serum creatine phosphokinase (CK) levels. Creatine phosphokinase is an enzyme found in muscles, and when muscles are damaged, CK is released into the bloodstream. Therefore, an increased serum CK level indicates muscle damage, and the nurse should assess the client for muscle tenderness or weakness, which are symptoms of this side eﬀect. Nausea and vomiting, excessive bruising, and peripheral edema are not typically associated with atorvastatin use.

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Correct Answer is B

Explanation

Cyclosporine is an immunosuppressive medication commonly used to prevent graft rejection after organ transplantation. St. John's Wort is known to induce cytochrome P450 enzymes, which can increase the metabolism and decrease the eﬀectiveness of many medications, including cyclosporine. This interaction can lead to decreased plasma concentrations of cyclosporine, which can increase the risk of graft rejection. Therefore, it is important to advise the client to discontinue the use of St. John's Wort and inform their healthcare provider about any herbal or supplement use to prevent potential interactions with prescribed medications. Options a, c, and d are not directly related to the client's current condition and are not as significant as option b.

A. Hearing has decreased. B. Decreased blood urea nitrogen. C. White blood cells count 6,000/mm3 (6x109/L). D. Reports of photophobia.

Correct Answer is A

Explanation

Gentamicin sulfate is an aminoglycoside antibiotic that can cause ototoxicity, which is damage to the inner ear leading to hearing loss or balance problems. Therefore, a decrease in hearing is an indication that the client may be experiencing an adverse eﬀect of gentamicin.

Option b, decreased blood urea nitrogen, is not an adverse eﬀect of gentamicin, but it may indicate improvement in kidney function, which can be a positive outcome of treatment.

Option c, a white blood cell count of 6,000/mm3 (6x109/L), is within the normal range and is not necessarily an adverse eﬀect of gentamicin.

Option d, photophobia, is not a common adverse eﬀect of gentamicin and may indicate a diﬀerent condition or medication eﬀect.

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A client taking atorvastatin becomes an increased serum creatine phosphokinase (CK) level. The nurse should assess the client for the onset of which problem?

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Naxlex Comprehensive Predictor Exams

Correct Answer is B

Explanation

A male client has been receiving the antibiotic gentamicin sulfate IV piggyback every 12 hours for several days. Which observations by the nurse indicate that the client may be experiencing an adverse eﬀect of gentamicin?

Correct Answer is A

Explanation

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A client taking atorvastatin becomes an increased serum creatine phosphokinase (CK) level.

The nurse should assess the client for the onset of which problem?