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A client is curious about the impact of chronic stress on the development of depression. Which statement accurately reflects the relationship between chronic stress and depression according to the text?

"Chronic stress can lead to hyperactivity of the HPA axis, resulting in elevated levels of cortisol that can support neuronal growth and survival.".

"Chronic stress can lead to hypoactivity of the HPA axis, resulting in reduced levels of cortisol that enhance neurogenesis and synaptic plasticity.".

"Chronic stress can lead to hyperactivity of the HPA axis, resulting in elevated levels of cortisol that can impair neurogenesis and synaptic plasticity.".

"Chronic stress can lead to hypoactivity of the HPA axis, resulting in reduced levels of cortisol that improve neurotrophic factors and cognitive function.".

Answer and Explanation

The Correct Answer is C

Choice A rationale:

Chronic stress is known to activate the Hypothalamic-Pituitary-Adrenal (HPA) axis, which leads to increased cortisol production. While cortisol is important for various physiological functions, chronic elevation of cortisol due to stress can actually have detrimental effects on the brain. Elevated cortisol levels have been associated with impaired neurogenesis (the formation of new neurons) and synaptic plasticity (the ability of synapses to change and adapt), both of which play crucial roles in maintaining cognitive function and mental health.

Choice B rationale:

This statement is not accurate. Chronic stress typically leads to hyperactivity, not hypoactivity, of the HPA axis, resulting in increased levels of cortisol. The increased cortisol levels can negatively impact neurogenesis and synaptic plasticity, which are key factors in depression and cognitive function.

Choice C rationale:

This is the correct statement. Chronic stress triggers hyperactivity of the HPA axis, causing elevated levels of cortisol. While cortisol is meant to help the body cope with stress in the short term, chronic elevation can lead to adverse effects on the brain. High cortisol levels have been linked to impaired neurogenesis and synaptic plasticity, contributing to the development of depression and cognitive deficits.

Choice D rationale:

This statement is not accurate. Chronic stress tends to lead to hyperactivity of the HPA axis and elevated cortisol levels. Reduced cortisol levels, as suggested in this choice, are not commonly associated with chronic stress and its impact on depression.

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Correct Answer is B

Explanation

Choice A rationale:

Pharmacological interventions involve the use of medications to treat conditions like Major Depressive Disorder (MDD). This does not involve stimulating the brain electrically or magnetically. While antidepressant medications can have an impact on neuronal activity and neuroplasticity, they are not classified as brain stimulation therapies.

Choice B rationale:

This is the correct answer. Electroconvulsive therapy (ECT) is a treatment modality that involves passing an electrical current through the brain to induce a controlled seizure. This has been found to be effective in cases of severe depression where other treatments have not worked. Other somatic therapies might include repetitive transcranial magnetic stimulation (rTMS) and vagus nerve stimulation (VNS), both of which involve modulating brain activity through electrical or magnetic means.

Choice C rationale:

Psychotherapeutic interventions involve talking therapies aimed at addressing psychological and emotional issues. These therapies do not directly involve electrical or magnetic stimulation of the brain. While they can certainly lead to changes in neuronal activity and neuroplasticity, they are not the primary modalities for brain stimulation.

Choice D rationale:

Cognitive-behavioral therapy (CBT) is a specific type of psychotherapeutic intervention that focuses on changing thought patterns and behaviors. While CBT can lead to changes in brain activity and neuroplasticity, it does not involve direct brain stimulation through electrical or magnetic means like ECT or rTMS.

A. Increased appetite. B. Hypertension. C. Insomnia. D. Excessive energy.

Correct Answer is C

Explanation

Choice A rationale:

Increased appetite is not a commonly associated side effect of antidepressant medications. In fact, some antidepressants can lead to decreased appetite or weight loss as side effects.

Choice B rationale:

Hypertension (high blood pressure) is generally not a common side effect of most antidepressant medications. However, there are specific cases where certain antidepressants might have an impact on blood pressure, but it's not a typical side effect across the board.

Choice C rationale:

This is the correct statement. Insomnia, or difficulty sleeping, is a commonly reported side effect of many antidepressant medications. It can disrupt sleep patterns and lead to increased sleep difficulties, which might exacerbate existing sleep problems or contribute to new ones.

Choice D rationale:

Excessive energy is not a common side effect associated with antidepressant use. Antidepressants typically work to regulate mood and alleviate symptoms of depression, and excessive energy would not align with the expected effects of these medications.

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A client is curious about the impact of chronic stress on the development of depression. Which statement accurately reflects the relationship between chronic stress and depression according to the text?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is discussing the various treatment approaches for Major Depressive Disorder (MDD) with a client. Which treatment modality involves stimulating the brain electrically or magnetically to induce changes in neuronal activity and neuroplasticity?

Correct Answer is B

Explanation

A client is concerned about the potential side effects of antidepressant medications. Which of the following side effects is commonly associated with antidepressant use?

Correct Answer is C

Explanation

A nurse is administering a depression assessment tool to a client. The tool evaluates mood, anxiety, insomnia, somatic symptoms, and other aspects of depression. Which assessment tool is the nurse most likely using?

A client is experiencing persistent feelings of sadness, guilt, and worthlessness. They also report significant weight loss and insomnia. The nurse suspects the client may have:

(Select All That Apply): A nurse is teaching a group of nursing students about the diagnostic criteria for major depressive disorder (MDD) according to DSM-5. Which of the following are part of the diagnostic criteria? Select all that apply.

A client is sharing their experiences with a nurse. The client states, "I just can't seem to enjoy anything anymore. Even activities I used to love don't bring me pleasure." This statement by the client is indicative of:

A client asks a nurse about the differences between major depressive disorder (MDD) and dysthymia. Which of the following responses by the nurse is accurate?

A client wants to understand the factors that contribute to the development of depression. Which of the following factors are mentioned in the text as potential contributors to depression?

A nurse is explaining the role of neurotransmitters in the pathophysiology of MDD to a group of nursing students. Which neurotransmitters are mentioned in the text as being involved in regulating mood, motivation, reward, cognition, and stress response?

(Select All That Apply): A nurse is providing care for a client with suspected major depressive disorder (MDD). Which of the following are risk factors for developing MDD? Select all that apply.