A nurse is discussing the theories that explain the biological basis of Major Depressive Disorder (MDD) with a group of nursing students. Which theory suggests that depression is caused by an imbalance of neurotransmitters in the brain that regulate mood, motivation, reward, cognition, and stress response?

Genetic theory.

Neuroendocrine theory.

Neurotransmitter theory.

Environmental theory.

Answer and Explanation

The Correct Answer is C

Choice A rationale:

Genetic theory suggests that a person's genetic makeup can predispose them to develop depression, but it does not specifically address the role of neurotransmitters in depression. While genetics can contribute to the risk of major depressive disorder (MDD), this choice doesn't focus on the neurotransmitter imbalances.

Choice B rationale:

Neuroendocrine theory pertains to the role of hormones in depression, particularly abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis. While hormones play a role in mood regulation, this theory does not primarily revolve around neurotransmitter imbalances.

Choice C rationale:

Neurotransmitter theory proposes that an imbalance of neurotransmitters, such as serotonin, norepinephrine, and dopamine, contributes to the development of major depressive disorder. This theory aligns with the idea that these neurotransmitters are responsible for regulating mood, motivation, reward, cognition, and stress response.

Choice D rationale:

Environmental theory suggests that external factors, such as life events and stressors, contribute to the development of depression. While environment can indeed influence depression, it does not specifically address the neurotransmitter imbalances that are central to this question.

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Correct Answer is ["C","D"]

Explanation

Choice A rationale:

Increased interest in activities is not consistent with the clinical presentation of MDD. In fact, a hallmark symptom of MDD is anhedonia, which involves a reduced interest or pleasure in most activities.

Choice B rationale:

Weight gain is not typically associated with MDD. In contrast, significant changes in appetite and weight loss are more common symptoms, often accompanied by feelings of worthlessness or guilt related to body image.

Choice C rationale:

Excessive guilt and self-blame are common cognitive and emotional symptoms of MDD. Individuals with MDD tend to have a negative self-perception and may blame themselves for their difficulties.

Choice D rationale:

Insomnia, or difficulty falling asleep or staying asleep, is a common sleep disturbance associated with MDD. Sleep problems can exacerbate the symptoms of depression and impact overall well-being.

Choice E rationale:

Elevated mood and increased energy are actually more indicative of conditions like bipolar disorder or manic episodes, where there are distinct periods of abnormally elevated mood, known as mania or hypomania.

A. "MDD is less severe than dysthymia but lasts for at least 2 years.". B. "Dysthymia is characterized by alternating episodes of mania and depression.". C. "Unlike MDD, dysthymia does not impair social or occupational functioning.". D. "Dysthymia is chronic and lasts for at least 2 years, but is less severe than MDD.".

Correct Answer is D

Explanation

Choice A rationale:

"MDD is less severe than dysthymia but lasts for at least 2 years." This statement is incorrect. Major Depressive Disorder (MDD) is characterized by the presence of a major depressive episode, which can be severe and persistent, lasting for at least two weeks. Dysthymia, on the other hand, is a chronic but milder form of depression that lasts for at least two years, not MDD.

Choice B rationale:

"Dysthymia is characterized by alternating episodes of mania and depression." This statement is incorrect. Dysthymia is a chronic mood disorder characterized by a persistent low mood and other depressive symptoms. It does not involve alternating episodes of mania and depression. Alternating episodes of mania and depression are characteristic of bipolar disorder, not dysthymia.

Choice C rationale:

"Unlike MDD, dysthymia does not impair social or occupational functioning." This statement is incorrect. Both Major Depressive Disorder (MDD) and dysthymia can significantly impair social, occupational, and other areas of functioning. In fact, dysthymia's chronic nature often leads to long-term impairment in various aspects of an individual's life, similar to MDD.

Choice D rationale:

"Dysthymia is chronic and lasts for at least 2 years, but is less severe than MDD." This statement is accurate. Dysthymia is a chronic form of depression that persists for at least two years. While it may not exhibit the same level of severity as a major depressive episode, its long-term nature can still have a substantial impact on an individual's quality of life. This distinguishes it from MDD, which can have episodic occurrences.

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Naxlex Comprehensive Predictor Exams

(Select All That Apply): A nurse is assessing a client for major depressive disorder (MDD). Which of the following signs and symptoms are consistent with the clinical presentation of MDD? Select all that apply.

Correct Answer is ["C","D"]

Explanation

A client asks a nurse about the differences between major depressive disorder (MDD) and dysthymia. Which of the following responses by the nurse is accurate?

Correct Answer is D

Explanation

A client is curious about the impact of chronic stress on the development of depression. Which statement accurately reflects the relationship between chronic stress and depression according to the text?

A nurse is assessing a client who has been experiencing persistent feelings of sadness, fatigue, and difficulty concentrating. The client denies any history of manic episodes. Which of the following conditions should the nurse consider as a possible differential diagnosis for this client?

(Select All That Apply): A nurse is discussing the psychosocial factors that can affect or be affected by depression with a client. Which of the following factors are considered psychosocial factors related to depression? Select all that apply.

A nurse is discussing the various treatment approaches for Major Depressive Disorder (MDD) with a client. Which treatment modality involves stimulating the brain electrically or magnetically to induce changes in neuronal activity and neuroplasticity?

A nurse is explaining the role of neurotransmitters in the pathophysiology of MDD to a group of nursing students. Which neurotransmitters are mentioned in the text as being involved in regulating mood, motivation, reward, cognition, and stress response?

(Select All That Apply): A nurse is educating a group of clients about the treatment approaches for MDD. Which of the following modalities are considered main treatment options for MDD according to the text? Select all that apply.

(Select All That Apply): A nurse is educating a client about the psychosocial factors that can influence or be influenced by depression. Which of the following factors are associated with depression and its effects on cognitive processes? Select all that apply.

A nurse is providing education to a group of nursing students about major depressive disorder (MDD). Which of the following statements accurately describes a characteristic of MDD?