A nurse is discussing the theories that explain the biological basis of Major Depressive Disorder (MDD) with a group of nursing students. Which theory suggests that depression is caused by an imbalance of neurotransmitters in the brain that regulate mood, motivation, reward, cognition, and stress response?
Genetic theory.
Neuroendocrine theory.
Neurotransmitter theory.
Environmental theory.
The Correct Answer is C
Choice A rationale:
Genetic theory suggests that a person's genetic makeup can predispose them to develop depression, but it does not specifically address the role of neurotransmitters in depression. While genetics can contribute to the risk of major depressive disorder (MDD), this choice doesn't focus on the neurotransmitter imbalances.
Choice B rationale:
Neuroendocrine theory pertains to the role of hormones in depression, particularly abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis. While hormones play a role in mood regulation, this theory does not primarily revolve around neurotransmitter imbalances.
Choice C rationale:
Neurotransmitter theory proposes that an imbalance of neurotransmitters, such as serotonin, norepinephrine, and dopamine, contributes to the development of major depressive disorder. This theory aligns with the idea that these neurotransmitters are responsible for regulating mood, motivation, reward, cognition, and stress response.
Choice D rationale:
Environmental theory suggests that external factors, such as life events and stressors, contribute to the development of depression. While environment can indeed influence depression, it does not specifically address the neurotransmitter imbalances that are central to this question.
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Correct Answer is C
Explanation
Choice A rationale:
Positive life events, although beneficial, are not typically considered contributors to the development of depression. Positive events generally have a positive impact on mental health and may even serve as protective factors against depression.
Choice B rationale:
High income is not commonly recognized as a direct contributor to depression. In fact, higher income can provide access to better resources and opportunities that might contribute to better mental health outcomes.
Choice C rationale:
Lack of social support is a well-established factor contributing to the development of depression. Social support plays a crucial role in buffering against stress and providing individuals with a sense of belonging and emotional connection. A lack of strong social ties can lead to feelings of isolation and increase vulnerability to depression.
Choice D rationale:
Optimistic thinking is typically considered a protective factor against depression rather than a contributor to its development. Optimistic thinking involves a positive outlook on life and the expectation of positive outcomes, which can act as a resilience factor against depressive symptoms.
Correct Answer is A
Explanation
Choice A rationale:
Patient Health naire (PHQ-9). The PHQ-9 is a commonly used depression assessment tool that evaluates a patient's mood and depressive symptoms. It consists of nine questions that correspond to the nine criteria for diagnosing major depressive disorder (MDD) according to the DSM-5. The tool assesses various aspects of depression, such as mood, sleep disturbances, appetite changes, and more. It's a self-report questionnaire that helps clinicians assess the severity of a patient's depression and track their progress over time.
Choice B rationale:
Hamilton Depression Rating Scale (HAM-D). The Hamilton Depression Rating Scale (HAM-D) is another widely used tool for assessing the severity of depressive symptoms in patients with mood disorders. It contains multiple items that evaluate various aspects of depression, such as mood, feelings of guilt, suicidal ideation, and more. Unlike the PHQ-9, the HAM-D is typically administered by a trained clinician and is more extensive, making it suitable for clinical research and diagnosis but potentially less practical for routine screening.
Choice C rationale:
Beck Depression Inventory (BDI). The Beck Depression Inventory (BDI) is a self-report questionnaire designed to assess the presence and severity of depressive symptoms in individuals. It consists of 21 multiple-choice questions that cover various emotional, cognitive, and physical symptoms of depression. The BDI is useful for assessing the intensity of depression and changes in symptom severity over time. While a valuable tool, it's not the assessment tool most likely used in this scenario.
Choice D rationale:
Mini-Mental State Examination (MMSE). The Mini-Mental State Examination (MMSE) is not an appropriate tool for assessing depression. Instead, it's a brief cognitive screening test used to assess cognitive impairment and cognitive decline in individuals, especially in older adults. It evaluates aspects such as orientation, memory, attention, language, and visuospatial skills. It is not designed to assess mood, anxiety, or other emotional aspects related to depression.
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