Which statement by a patient makes the nurse aware of a need for further education about drug resistance in antimicrobial therapy?
"The antibiotic I have been taking doesn't work as well as it used to."
"The bacteria in my body have become resilient."
"Over time, an organism that had once been highly sensitive to an antibiotic may become less susceptible, or it may lose drug sensitivity entirely."
"My body has become resistant to the antibiotic."
The Correct Answer is D
A. "The antibiotic I have been taking doesn't work as well as it used to."
This statement shows awareness of decreased effectiveness, which can occur due to drug resistance. Bacteria can become resistant to antibiotics, leading to reduced efficacy of the medication over time.
B. "The bacteria in my body have become resilient."
This statement correctly attributes resistance to the bacteria. Resilience in this context means that bacteria have developed mechanisms to survive the effects of antibiotics, making the treatment less effective.
C. "Over time, an organism that had once been highly sensitive to an antibiotic may become less susceptible, or it may lose drug sensitivity entirely."
This statement accurately describes the concept of drug resistance. Bacteria can lose sensitivity to antibiotics, rendering the drugs ineffective against them.
D. "My body has become resistant to the antibiotic."
This statement is incorrect. It's the bacteria that develop resistance, not the patient's body. Patients don't become resistant to antibiotics; instead, bacteria evolve and adapt, making the drugs less effective against them.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. "Tetracycline inhibits protein synthesis."
Explanation: Tetracycline antibiotics interfere with bacterial protein synthesis by binding to the bacterial ribosomes. This binding prevents the attachment of transfer RNA (tRNA) to the messenger RNA (mRNA) complex, effectively inhibiting the production of proteins that are crucial for bacterial growth and replication.
B. "Tetracycline blocks RNA synthesis."
Explanation: This statement is incorrect. Tetracycline primarily affects protein synthesis, not RNA synthesis. It doesn't block the creation of RNA molecules in bacteria.
C. "Tetracycline degrades the bacterial cell wall."
Explanation: This statement is incorrect. Tetracycline antibiotics do not target bacterial cell walls. Agents like penicillins and cephalosporins are examples of antibiotics that disrupt bacterial cell walls.
D. "Tetracycline binds to magnesium ions."
Explanation: This statement is incorrect. Tetracycline does bind to certain metal ions, but it's not primarily through magnesium ions. The binding to bacterial ribosomes is a key mechanism of action for tetracyclines.

Correct Answer is D
Explanation
A. Reddened tongue and gums: This side effect is not typically associated with ampicillin. However, certain medications or medical conditions can cause changes in oral tissues, leading to redness in the tongue and gums.
B. Digit numbness and tingling: Ampicillin does not commonly cause numbness and tingling in the fingers and toes. These symptoms can be associated with neurological issues or circulatory problems.
C. Bruising and petechiae: These symptoms can indicate bleeding disorders or low platelet count and are not usually caused by ampicillin. It's essential to investigate further if a patient experiences unexplained bruising or petechiae.
D. Skin rash and loose stools: Skin rash is a known side effect of penicillin-type antibiotics, including ampicillin. Loose stools or diarrhea can also occur due to disruption of the gut flora caused by the antibiotic. Patients should be aware of these possibilities and report any severe or persistent symptoms to their healthcare provider.
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